CatLogenzyme kinetics catalog

Values CatLog read from this paper

Allostery and Hysteresis Are Coupled in Human UDP-Glucose Dehydrogenase

PMID 27966912doi:10.1021/acs.biochem.6b01044Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (13 values) from this paper: UDP-glucose dehydrogenase (hUGDH) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.1.1.22

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UDP-glucose dehydrogenase (hUGDH)Homo sapiensNAD+0.76——pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)Homo sapiensUDP-glucose2.5 mM NAD+ (saturating); UDP-Glc saturation curve0.550.009757 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)Homo sapiensUDP-glucose0.550.009558 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A136MHomo sapiensNAD+0.830.099.2 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A136MHomo sapiensUDP-glucose2.5 mM NAD+ (saturating); UDP-Glc saturation curve0.730.00726100 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A136MHomo sapiensUDP-glucoseglobal fit of UDP-Glc saturation curves at 00.740.00734100 calc.pH 7.5, 25 °COpen
UDP-glucose dehydrogenase (hUGDH)variant A136MHomo sapiensUDP-glucosewith 60 µM UDP-Xyl (inhibitor); separate experiment0.850.0063130 calc.pH 7.5, 25 °COpen