CatLogenzyme kinetics catalog

Values CatLog read from this paper

The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site

PMID 17578897doi:10.1124/mol.107.036871Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 16 records (16 values) from this paper: UGT1A6, UGT1A9 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.1.17

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
UGT1A6Homo sapiens1-naphthol—0.0027—pH 7.4, 37 °COpen
UGT1A6Homo sapiens4-methylumbelliferone—0.17—pH 7.4, 37 °COpen
UGT1A6Homo sapiens7-hydroxy-6-methoxy-2H-1-benzopyran-2-one—0.33—pH 7.4, 37 °COpen
UGT1A6Homo sapiensUDP-glucuronic acid—0.29—pH 7.4, 37 °COpen
UGT1A6variant E379AHomo sapiens1-naphthol—0.048—pH 7.4, 37 °COpen
UGT1A6variant E379AHomo sapiens4-methylumbelliferone—0.58—pH 7.4, 37 °COpen
UGT1A6variant E379AHomo sapiens7-hydroxy-6-methoxy-2H-1-benzopyran-2-one—1.47—pH 7.4, 37 °COpen
UGT1A6variant E379AHomo sapiensUDP-glucuronic acid—7.64—pH 7.4, 37 °COpen
UGT1A6variant H371AHomo sapiens1-naphthol—0.083—pH 7.4, 37 °COpen
UGT1A6variant H371AHomo sapiens4-methylumbelliferone—0.66—pH 7.4, 37 °COpen
UGT1A6variant H371AHomo sapiens7-hydroxy-6-methoxy-2H-1-benzopyran-2-one—1.71—pH 7.4, 37 °COpen
UGT1A6variant H371AHomo sapiensUDP-glucuronic acid—3.88—pH 7.4, 37 °COpen
UGT1A9Homo sapiens7-hydroxy-6-methoxy-2H-1-benzopyran-2-one—0.08—pH 7.4, 37 °COpen
UGT1A9Homo sapiensUDP-glucuronic acid—0.21—pH 7.4, 37 °COpen
UGT1A9variant H369AHomo sapiens7-hydroxy-6-methoxy-2H-1-benzopyran-2-one—1.64—pH 7.4, 37 °COpen
UGT1A9variant H369AHomo sapiensUDP-glucuronic acid—6.47—pH 7.4, 37 °COpen