Values CatLog read from this paper
Proposal of metagenomic-origin LRA-5 as a precursor of active β-lactamases through Tyr69Gln and Val166Glu amino acid substitutions: a functional and structural analysis
PMID 41312992doi:10.1128/aac.00675-25Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 16 records (46 values) from this paper: LRA-5.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| LRA-5 | — | ampicillin | 0.01 | 0.065 | 0.154 | pH 7.5, 22 °C | Open record: LRA-5, ampicillin |
| LRA-5 | — | aztreonam | 2 × 10⁻⁵ | — | — | pH 7.5, 22 °C | Open record: LRA-5, aztreonam |
| LRA-5 | — | cefepime | 0.02 | 0.01 | 2 | pH 7.5, 22 °C | Open record: LRA-5, cefepime |
| LRA-5 | — | ceftazidime | 5 × 10⁻⁵ | 0.006 | 0.0083 | pH 7.5, 22 °C | Open record: LRA-5, ceftazidime |
| LRA-5 | — | ceftriaxone | 3.6 × 10⁻⁶ | 0.011 | 3.2 × 10⁻⁴ | pH 7.5, 22 °C | Open record: LRA-5, ceftriaxone |
| LRA-5 | — | cephalothin | 0.005 | 0.035 | 0.143 | pH 7.5, 22 °C | Open record: LRA-5, cephalothin |
| LRA-5 | — | nitrocefin | 0.045 | 0.008 | 5.6 | pH 7.5, 22 °C | Open record: LRA-5, nitrocefin |
| LRA-5variant Y69Q/V166E | — | ampicillin | 0.002 | 0.004 | 0.5 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, ampicillin |
| LRA-5variant Y69Q/V166E | — | aztreonam | 1.4 × 10⁻⁴ | 0.019 | 0.0074 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, aztreonam |
| LRA-5variant Y69Q/V166E | — | cefepime | 0.4 | 0.108 | 3.7 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, cefepime |
| LRA-5variant Y69Q/V166E | — | ceftazidime | 0.043 | 0.086 | 0.5 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, ceftazidime |
| LRA-5variant Y69Q/V166E | — | ceftriaxone | 0.107 | 0.029 | 3.69 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, ceftriaxone |
| LRA-5variant Y69Q/V166E | — | cephalothin | 0.025 | 0.014 | 1.785 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, cephalothin |
| LRA-5variant Y69Q/V166E | — | imipenem | 0.006 | 0.003 | 1.917 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, imipenem |
| LRA-5variant Y69Q/V166E | — | meropenem | 0.003 | 0.005 | 0.6 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, meropenem |
| LRA-5variant Y69Q/V166E | — | nitrocefin | 4.8 | 0.032 | 150 | pH 7.5, 22 °C | Open record: LRA-5 variant Y69Q/V166E, nitrocefin |