Values CatLog read from this paper

Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria

PMID 21998747doi:10.1371/journal.pone.0026021Open in Browse

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CatLog read 10 records (30 values) from this paper: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 4.1.3.16

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	6.1	0.011	555	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA), 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant N78A	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	7.6	0.066	115	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant N78A, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant N78Q	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	6.2	0.281	22	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant N78Q, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant N78T	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	4	0.016	250	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant N78T, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant S198A	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	2.4	0.044	55	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant S198A, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant S198T	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	7.8	0.077	101	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant S198T, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant S77A	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	2.5	0.084	30	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant S77A, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant S77T	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	0.8	0.058	14	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant S77T, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant S77V	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	1.2	0.082	15	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant S77V, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)
4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA)variant Y140F	Homo sapiens	4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)	5.2	0.008	650	pH 8.5, 37 °C	Open record: 4-hydroxy-2-oxoglutarate aldolase (human HOGA, hHOGA) variant Y140F, 4-hydroxy-2-oxoglutarate (racemic mixture of R- and S-forms)