Values CatLog read from this paper
Augmented intrinsic activity of Factor VIIa by replacement of residues 305, 314, 337 and 374: evidence of two unique mutational mechanisms of activity enhancement
PMID 14686879doi:10.1042/bj20031596Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (24 values) from this paper: coagulation Factor VIIa (FVIIa) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| coagulation Factor VIIa (FVIIa) | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidefree enzyme; no tissue factor | — | 10.4 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa), D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa) | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilide | — | 1.6 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa), D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa) | Homo sapiens | Factor Xfree enzyme; no tissue factor | 1.5 × 10⁻⁴ | 0.0044 | 0.034 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa), Factor X |
| coagulation Factor VIIa (FVIIa) | Homo sapiens | Factor X | 0.0077 | 0.003 | 2.6 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa), Factor X |
| coagulation Factor VIIa (FVIIa)variant L305V/S314E/K337A/F374Y | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidefree enzyme; no tissue factor | — | 1.9 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa) variant L305V/S314E/K337A/F374Y, D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa)variant L305V/S314E/K337A/F374Y | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilide | — | 0.85 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa) variant L305V/S314E/K337A/F374Y, D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa)variant L305V/S314E/K337A/F374Y | Homo sapiens | Factor Xfree enzyme; no tissue factor | 0.0012 | 0.0027 | 0.44 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa) variant L305V/S314E/K337A/F374Y, Factor X |
| coagulation Factor VIIa (FVIIa)variant L305V/S314E/K337A/F374Y | Homo sapiens | Factor X | 0.007 | 0.0021 | 3.3 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa) variant L305V/S314E/K337A/F374Y, Factor X |
| coagulation Factor VIIa (FVIIa)variant V158D/E296V/M298Q | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilidefree enzyme; no tissue factor | — | 6.7 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa) variant V158D/E296V/M298Q, D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa)variant V158D/E296V/M298Q | Homo sapiens | D-Ile-Pro-Arg-p-nitroanilide | — | 1.7 | — | pH 7.4 | Open record: coagulation Factor VIIa (FVIIa) variant V158D/E296V/M298Q, D-Ile-Pro-Arg-p-nitroanilide |
| coagulation Factor VIIa (FVIIa)variant V158D/E296V/M298Q | Homo sapiens | Factor Xfree enzyme; no tissue factor | 0.0053 | 0.0018 | 2.9 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa) variant V158D/E296V/M298Q, Factor X |
| coagulation Factor VIIa (FVIIa)variant V158D/E296V/M298Q | Homo sapiens | Factor X | 0.024 | 0.0021 | 11.4 | pH 7.4, 22 °C | Open record: coagulation Factor VIIa (FVIIa) variant V158D/E296V/M298Q, Factor X |