CatLogenzyme kinetics catalog

Values CatLog read from this paper

Compromised catalysis and potential folding defects in in vitro studies of missense mutants associated with hereditary phosphoglucomutase 1 deficiency

PMID 25288802doi:10.1074/jbc.m114.597914Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 10 records (30 values) from this paper: phosphoglucomutase 1 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 5.4.2.2

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
phosphoglucomutase 1Homo sapiensalpha-D-glucose 1-phosphate1430.081.8 × 10³pH 7.4, 25 °COpen
phosphoglucomutase 1variant D263GHomo sapiensalpha-D-glucose 1-phosphate30.11526pH 7.4, 25 °COpen
phosphoglucomutase 1variant D263YHomo sapiensalpha-D-glucose 1-phosphate1.540.179.1pH 7.4, 25 °COpen
phosphoglucomutase 1variant D62HHomo sapiensalpha-D-glucose 1-phosphate0.1970.02338.5pH 7.4, 25 °COpen
phosphoglucomutase 1variant G121RHomo sapiensalpha-D-glucose 1-phosphate0.3680.0566.6pH 7.4, 25 °COpen
phosphoglucomutase 1variant K68MHomo sapiensalpha-D-glucose 1-phosphate1530.06382.4 × 10³pH 7.4, 25 °COpen
phosphoglucomutase 1variant R221CHomo sapiensalpha-D-glucose 1-phosphate2000.0942.1 × 10³pH 7.4, 25 °COpen
phosphoglucomutase 1variant T115AHomo sapiensalpha-D-glucose 1-phosphate360.041880pH 7.4, 25 °COpen
phosphoglucomutase 1variant T19AHomo sapiensalpha-D-glucose 1-phosphate0.6850.135.3pH 7.4, 25 °COpen
phosphoglucomutase 1variant Y420HHomo sapiensalpha-D-glucose 1-phosphate1620.0752.1 × 10³pH 7.4, 25 °COpen