Values CatLog read from this paper
Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes
PMID 12767217doi:10.1021/bi027391+Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (20 values) from this paper: CYP2C5, CYP2C18, CYP2C19 and 2 more from Homo sapiens, Oryctolagus cuniculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 1.14.14.1, EC 1.14.14.51, EC 1.14.14.52, EC 1.14.14.53, EC 1.14.14.75
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP2C18 | Homo sapiens | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 0.67 | 0.005 | 130 | pH 7.4, 28 °C | Open record: CYP2C18, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |
| CYP2C19 | Homo sapiens | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 0.27 | 0.008 | 33 | pH 7.4, 28 °C | Open record: CYP2C19, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |
| CYP2C5variant CYP2C5/3LVdH | Oryctolagus cuniculus | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 0.67 | 0.01 | 67 | pH 7.6, 37 °C | Open record: CYP2C5 variant CYP2C5/3LVdH, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |
| CYP2C5variant CYP2C5dH | Oryctolagus cuniculus | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 1.5 | 0.013 | 120 | pH 7.6, 37 °C | Open record: CYP2C5 variant CYP2C5dH, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |
| CYP2C5variant CYP2C5dH | Oryctolagus cuniculus | progesteronein the text | 0.2 | — | — | pH 7.6, 37 °C | Open record: CYP2C5 variant CYP2C5dH, progesterone |
| CYP2C5variant CYP2C5dH | Oryctolagus cuniculus | progesteroneTable 1 | — | 0.004 | — | pH 7.6, 37 °C | Open record: CYP2C5 variant CYP2C5dH, progesterone |
| CYP2C8 | Homo sapiens | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 0.067 | 0.04 | 1.7 | pH 7.4, 28 °C | Open record: CYP2C8, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |
| CYP2C9 | Homo sapiens | 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide | 0.58 | 0.012 | 50 | pH 7.4, 28 °C | Open record: CYP2C9, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide |