CatLogenzyme kinetics catalog

EC 1.14.14.51: (S)-limonene 6-monooxygenase

OxidoreductasesOpen in Browse

CatLog read 19 records for EC 1.14.14.51 from 4 papers, for 1 organism. Names in these papers: CYP2C19, CYP2C9, CYP2C9*1.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 11 records for EC 1.14.14.51 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.14.51 in Browse.

Papers

PaperOrganismsRecords
The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthionHomo sapiens10
Role of cytochrome P450 enzymes in fimasartan metabolism in vitroHomo sapiens4
Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerateHomo sapiens3
Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymesHomo sapiens2

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
CYP2C19Homo sapiens(alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate1.0270.009110 calc.pH 7.4, 37 °CPMID 17576809Open
CYP2C19Homo sapiens(alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate1.0730.0041260 calc.pH 7.4, 37 °CPMID 17576809Open
CYP2C19Homo sapiens4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide0.270.00833pH 7.4, 28 °CPMID 12767217Open
CYP2C19Homo sapiensfenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH—0.0024—pH 7.4, 37 °CPMID 18845175Open
CYP2C19Homo sapiensfenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH—0.0044—pH 7.4, 37 °CPMID 18845175Open
CYP2C19Homo sapiensfenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH0.0217—8.8pH 7.4, 37 °CPMID 18845175Open
CYP2C19Homo sapiensfenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH0.127—28pH 7.4, 37 °CPMID 18845175Open
CYP2C19Homo sapiensfenthion sulfoxideFEN-sulfoxide 1.5-25 µM; 37 °C with shaking—0.018—pH 7.4, 37 °CPMID 18845175Open
CYP2C19Homo sapiensfenthion sulfoxide2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH0.013—0.67pH 7.4, 37 °CPMID 18845175Open
CYP2C9Homo sapiens2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-{[2-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}pyrimidine-4(3H)-oneformation of FMS S-oxide0.0780.0223.5pH 7.4, 37 °CPMID 29596975Open
CYP2C9Homo sapiens2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-{[2-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}pyrimidine-4(3H)-oneformation of 1-OH butyl FMS0.0980.7710.127pH 7.4, 37 °CPMID 29596975Open
CYP2C9Homo sapiens2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-{[2-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}pyrimidine-4(3H)-oneformation of 2-OH or 3-OH butyl FMS0.00830.01220.68pH 7.4, 37 °CPMID 29596975Open
CYP2C9Homo sapiens2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-{[2-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}pyrimidine-4(3H)-oneformation of 4-OH butyl FMS0.0140.02410.58pH 7.4, 37 °CPMID 29596975Open
CYP2C9Homo sapiens4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide0.580.01250pH 7.4, 28 °CPMID 12767217Open
CYP2C9Homo sapiensfenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH—0.012—pH 7.4, 37 °CPMID 18845175Open
CYP2C9Homo sapiensfenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH—0.006—pH 7.4, 37 °CPMID 18845175Open
CYP2C9Homo sapiensfenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH0.023—2pH 7.4, 37 °CPMID 18845175Open
CYP2C9Homo sapiensfenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH0.027—4.2pH 7.4, 37 °CPMID 18845175Open
CYP2C9*1Homo sapiens(alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate1.330.024354.7 calc.pH 7.4, 37 °CPMID 17576809Open