Values CatLog read from this paper
Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate
PMID 17576809doi:10.1124/dmd.107.015388Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (25 values) from this paper: CYP2C11, CYP2C19, CYP2C6 and 4 more from Rattus norvegicus, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 11 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
EC 1.14.14.1, EC 1.14.14.51, EC 1.14.14.52, EC 1.14.14.53, EC 1.14.14.75, EC 3.1.1.1
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP2C11 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 3.43 | 0.0319 | 108 calc. | pH 7.4, 37 °C | Open record: CYP2C11, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |
| CYP2C11 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 3.657 | 0.0335 | 109 calc. | pH 7.4, 37 °C | Open record: CYP2C11, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| CYP2C19 | Homo sapiens | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 1.027 | 0.009 | 110 calc. | pH 7.4, 37 °C | Open record: CYP2C19, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |
| CYP2C19 | Homo sapiens | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 1.073 | 0.0041 | 260 calc. | pH 7.4, 37 °C | Open record: CYP2C19, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| CYP2C6 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 2.5 | 0.0216 | 120 calc. | pH 7.4, 37 °C | Open record: CYP2C6, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |
| CYP2C6 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 2.637 | 0.0382 | 69.0 calc. | pH 7.4, 37 °C | Open record: CYP2C6, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| CYP2C8 | Homo sapiens | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 0.712 | 0.0102 | 69.8 calc. | pH 7.4, 37 °C | Open record: CYP2C8, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |
| CYP2C8 | Homo sapiens | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 0.987 | 0.0191 | 51.7 calc. | pH 7.4, 37 °C | Open record: CYP2C8, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| CYP2C9*1 | Homo sapiens | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 1.33 | 0.0243 | 54.7 calc. | pH 7.4, 37 °C | Open record: CYP2C9*1, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| CYP3A2 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 0.432 | 0.0064 | 67 calc. | pH 7.4, 37 °C | Open record: CYP3A2, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |
| CYP3A2 | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate | 0.658 | 0.0043 | 150 calc. | pH 7.4, 37 °C | Open record: CYP3A2, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate |
| serum carboxylesterase (CE) | Rattus norvegicus | (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate | 0.008 | 0.0126 | 0.63 | pH 7.4, 37 °C | Open record: serum carboxylesterase (CE), (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate |