EC 1.14.14.75: fenbendazole monooxygenase (4'-hydroxylating)

OxidoreductasesOpen in Browse

CatLog read 9 records for EC 1.14.14.75 from 3 papers, for 1 organism. Names in these papers: CYP2C19.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

Papers with records for EC 1.14.14.75
Paper	Organisms	Records
The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion	Homo sapiens	6
Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate	Homo sapiens	2
Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes	Homo sapiens	1

Records

Records for EC 1.14.14.75 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
CYP2C19	Homo sapiens	(alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate	1.027	0.009	110 calc.	pH 7.4, 37 °C	PMID 17576809	Open record: CYP2C19, (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate
CYP2C19	Homo sapiens	(alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate	1.073	0.0041	260 calc.	pH 7.4, 37 °C	PMID 17576809	Open record: CYP2C19, (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate
CYP2C19	Homo sapiens	4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide	0.27	0.008	33	pH 7.4, 28 °C	PMID 12767217	Open record: CYP2C19, 4-methyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide
CYP2C19	Homo sapiens	fenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH	—	0.0024	—	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion
CYP2C19	Homo sapiens	fenthionFEN 0.5-100 µM added in 12 µL methanol; cosubstrate NADPH	—	0.0044	—	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion
CYP2C19	Homo sapiens	fenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH	0.0217	—	8.8	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion
CYP2C19	Homo sapiens	fenthion2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH	0.127	—	28	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion
CYP2C19	Homo sapiens	fenthion sulfoxideFEN-sulfoxide 1.5-25 µM; 37 °C with shaking	—	0.018	—	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion sulfoxide
CYP2C19	Homo sapiens	fenthion sulfoxide2 mM glucose-6-phosphate; 2 mM MgCl2; 2-4 U/ml G6PDH	0.013	—	0.67	pH 7.4, 37 °C	PMID 18845175	Open record: CYP2C19, fenthion sulfoxide

CatLog snapshot Oct 24, 2026 (data ID 660092338b). CatLog's compilation is free to reuse under CC BY 4.0; records from a database keep its license. How to cite.