CatLogenzyme kinetics catalog

Values CatLog read from this paper

Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3

PMID 29705271doi:10.1016/j.abb.2018.04.019Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 52 records (52 values) from this paper: SULT1A3 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.8.2.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
SULT1A3Homo sapiensacetaminophen—0.63—pH 7.4, 37 °COpen
SULT1A3Homo sapiensmorphine—4.6—pH 7.4, 37 °COpen
SULT1A3Homo sapiensO-desmethyl tramadol—0.46—pH 7.4, 37 °COpen
SULT1A3Homo sapienstapentadol—0.15—pH 7.4, 37 °COpen
SULT1A3variant K234NHomo sapiensacetaminophen—0.63—pH 7.4, 37 °COpen
SULT1A3variant K234NHomo sapiensmorphine—8.3—pH 7.4, 37 °COpen
SULT1A3variant K234NHomo sapiensO-desmethyl tramadol—0.58—pH 7.4, 37 °COpen
SULT1A3variant K234NHomo sapienstapentadol—0.55—pH 7.4, 37 °COpen
SULT1A3variant N235THomo sapiensacetaminophen—4.5—pH 7.4, 37 °COpen
SULT1A3variant N235THomo sapiensmorphine—10—pH 7.4, 37 °COpen
SULT1A3variant N235THomo sapiensO-desmethyl tramadol—0.8—pH 7.4, 37 °COpen
SULT1A3variant N235THomo sapienstapentadol—0.84—pH 7.4, 37 °COpen
SULT1A3variant P101HHomo sapiensacetaminophen—0.43—pH 7.4, 37 °COpen
SULT1A3variant P101HHomo sapiensmorphine—3.8—pH 7.4, 37 °COpen
SULT1A3variant P101HHomo sapiensO-desmethyl tramadol—0.27—pH 7.4, 37 °COpen
SULT1A3variant P101HHomo sapienstapentadol—0.09—pH 7.4, 37 °COpen
SULT1A3variant P101LHomo sapiensacetaminophen—0.98—pH 7.4, 37 °COpen
SULT1A3variant P101LHomo sapiensmorphine—6.4—pH 7.4, 37 °COpen
SULT1A3variant P101LHomo sapiensO-desmethyl tramadol—0.54—pH 7.4, 37 °COpen
SULT1A3variant P101LHomo sapienstapentadol—0.24—pH 7.4, 37 °COpen
SULT1A3variant P10LHomo sapiensacetaminophen—0.97—pH 7.4, 37 °COpen
SULT1A3variant P10LHomo sapiensmorphine—5.9—pH 7.4, 37 °COpen
SULT1A3variant P10LHomo sapiensO-desmethyl tramadol—0.53—pH 7.4, 37 °COpen
SULT1A3variant P10LHomo sapienstapentadol—0.32—pH 7.4, 37 °COpen
SULT1A3variant R144CHomo sapiensacetaminophen—1.97—pH 7.4, 37 °COpen
SULT1A3variant R144CHomo sapiensmorphine—7.2—pH 7.4, 37 °COpen
SULT1A3variant R144CHomo sapiensO-desmethyl tramadol—0.35—pH 7.4, 37 °COpen
SULT1A3variant R144CHomo sapienstapentadol—0.11—pH 7.4, 37 °COpen
SULT1A3variant R9CHomo sapiensacetaminophen—1.25—pH 7.4, 37 °COpen
SULT1A3variant R9CHomo sapiensmorphine—5—pH 7.4, 37 °COpen
SULT1A3variant R9CHomo sapiensO-desmethyl tramadol—0.51—pH 7.4, 37 °COpen
SULT1A3variant R9CHomo sapienstapentadol—0.34—pH 7.4, 37 °COpen
SULT1A3variant S290THomo sapiensacetaminophen—1.05—pH 7.4, 37 °COpen
SULT1A3variant S290THomo sapiensmorphine—6.2—pH 7.4, 37 °COpen
SULT1A3variant S290THomo sapiensO-desmethyl tramadol—0.48—pH 7.4, 37 °COpen
SULT1A3variant S290THomo sapienstapentadol—0.21—pH 7.4, 37 °COpen
SULT1A3variant S8PHomo sapiensacetaminophen—0.67—pH 7.4, 37 °COpen
SULT1A3variant S8PHomo sapiensmorphine—7.8—pH 7.4, 37 °COpen
SULT1A3variant S8PHomo sapiensO-desmethyl tramadol—0.66—pH 7.4, 37 °COpen
SULT1A3variant S8PHomo sapienstapentadol—0.48—pH 7.4, 37 °COpen
SULT1A3variant T7PHomo sapiensacetaminophen—0.73—pH 7.4, 37 °COpen
SULT1A3variant T7PHomo sapiensmorphine—5.7—pH 7.4, 37 °COpen
SULT1A3variant T7PHomo sapiensO-desmethyl tramadol—0.5—pH 7.4, 37 °COpen
SULT1A3variant T7PHomo sapienstapentadol—0.19—pH 7.4, 37 °COpen
SULT1A3variant V15MHomo sapiensacetaminophen—0.72—pH 7.4, 37 °COpen
SULT1A3variant V15MHomo sapiensmorphine—5—pH 7.4, 37 °COpen
SULT1A3variant V15MHomo sapiensO-desmethyl tramadol—0.57—pH 7.4, 37 °COpen
SULT1A3variant V15MHomo sapienstapentadol—0.38—pH 7.4, 37 °COpen
SULT1A3variant V18FHomo sapiensacetaminophen—0.78—pH 7.4, 37 °COpen
SULT1A3variant V18FHomo sapiensmorphine—5.7—pH 7.4, 37 °COpen
SULT1A3variant V18FHomo sapiensO-desmethyl tramadol—0.5—pH 7.4, 37 °COpen
SULT1A3variant V18FHomo sapienstapentadol—0.32—pH 7.4, 37 °COpen