CatLogenzyme kinetics catalog

Values CatLog read from this paper

Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2

PMID 21291263doi:10.1021/bi1014453Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 64 records (182 values) from this paper: PTP1B, SHP-2, SHP-1 and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.3.48

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
PTP1B—Ac-AAAAApYEEVH-NH2340.0321.1 × 10³pH 7.4Open
PTP1B—Ac-AAAAApYRHRR-NH2330.234140pH 7.4Open
PTP1B—Ac-AKFEDTpYAA-NH2170.00354.9 × 10³pH 7.4Open
PTP1B—Ac-ApYFPIWpYAA-NH2200.00355.9 × 10³pH 7.4Open
PTP1B—Ac-ApYpYEVSpYAA-NH2190.0029.5 × 10³pH 7.4Open
PTP1B—Ac-ApYpYWTApYAA-NH2260.00171.51 × 10⁴pH 7.4Open
PTP1B—Ac-ApYYAESpYAA-NH2160.00315.1 × 10³pH 7.4Open
PTP1B—Ac-ARKRIpYAA-NH2——140pH 7.4Open
PTP1B—Ac-ASSDDpYAA-NH2330.0181.8 × 10³pH 7.4Open
PTP1B—Ac-ATADVpYAA-NH2310.0122.5 × 10³pH 7.4Open
PTP1B—Ac-AVpYADHpYAA-NH2240.00317.8 × 10³pH 7.4Open
PTP1B—Ac-AVWEFpYpYAA-NH2260.00298.9 × 10³pH 7.4Open
PTP1B—Ac-AWSpYADpYAA-NH2219.1 × 10⁻⁴2.35 × 10⁴pH 7.4Open
PTP1B—Ac-AYTEpYTpYAA-NH2170.00296 × 10³pH 7.4Open
PTP1B—Ac-DAADVpYAA-NH2320.013.1 × 10³pH 7.4Open
PTP1B—Ac-DTAAVpYAA-NH2320.0181.8 × 10³pH 7.4Open
PTP1B—Ac-DTADApYAA-NH2380.0351.1 × 10³pH 7.4Open
PTP1B—Ac-DTADVpYAA-NH2310.00893.5 × 10³pH 7.4Open
PTP1B—Ac-DTADVpYDWEF-NH2290.00525.8 × 10³pH 7.4Open
PTP1B—Ac-DTADVpYGEFTI-NH2330.0074.8 × 10³pH 7.4Open
PTP1B—Ac-RRISTpYAA-NH2780.09870pH 7.4Open
PTP1B—Ac-RTLAApYAAAA-NH2330.066510pH 7.4Open
PTP1B—Ac-RTLAApYEEVH-NH2360.043840pH 7.4Open
PTP1B—Ac-RTLAApYRFQK-NH2370.165220pH 7.4Open
RPTPα—4-nitrophenyl phosphate0.542.70.19Open
RPTPα—Ac-AAAAApYEEVH-NH2——39pH 7.4Open
RPTPα—Ac-AAAAApYRHRR-NH2302.612pH 7.4Open
RPTPα—Ac-ARKRIpYAA-NH2390.4980pH 7.4Open
RPTPα—Ac-ASSDDpYAA-NH2——13pH 7.4Open
RPTPα—Ac-EADTApYAA-NH2261.419pH 7.4Open
RPTPα—Ac-RRISTpYAA-NH2491.241pH 7.4Open
RPTPα—Ac-SASASpYSASA-NH2230.5343pH 7.4Open
RPTPα—Ac-WDEDFpYSASA-NH2——69pH 7.4Open
RPTPα—phenyl phosphate——0.02Open
SHP-1—Ac-AKFEDTpYAA-NH2190.058340pH 7.4Open
SHP-1—Ac-AVWEFpYpYAA-NH2240.00753.3 × 10³pH 7.4Open
SHP-1—Ac-AWSpYADpYAA-NH2130.022580pH 7.4Open
SHP-1—Ac-AYTEpYTpYAA-NH2170.00911.9 × 10³pH 7.4Open
SHP-1—Ac-EIFDFpYAA-NH2320.0271.2 × 10³pH 7.4Open
SHP-1—Ac-FDIDIpYAA-NH2330.0132.5 × 10³pH 7.4Open
SHP-1—Ac-FYDIDpYAA-NH2660.0282.4 × 10³pH 7.4Open
SHP-1—Ac-SASASpYDWEF-NH2120.048250pH 7.4Open
SHP-1—Ac-SASASpYSASA-NH2261.9913pH 7.4Open
SHP-1—Ac-WAGDDpYAA-NH2570.0451.3 × 10³pH 7.4Open
SHP-1—Ac-WDEDFpYDWEF-NH2750.00322.3 × 10⁴pH 7.4Open
SHP-1—Ac-WDEDFpYRWKF-NH2420.15280pH 7.4Open
SHP-1—Ac-WDEDFpYSASA-NH2370.053700pH 7.4Open
SHP-1—Ac-WRKRFpYDWEF-NH21.70.782.2pH 7.4Open
SHP-2—Ac-ADEDFpYAA-NH2280.034820pH 7.4Open
SHP-2—Ac-DAEDFpYAA-NH2300.0281.1 × 10³pH 7.4Open
SHP-2—Ac-DFEDFpYAA-NH2370.0231.6 × 10³pH 7.4Open
SHP-2—Ac-DWEDFpYAA-NH2300.0171.7 × 10³pH 7.4Open
SHP-2—Ac-EIFDFpYAA-NH2260.054480pH 7.4Open
SHP-2—Ac-FDEDFpYAA-NH2300.0311 × 10³pH 7.4Open
SHP-2—Ac-FDIDIpYAA-NH2300.039770pH 7.4Open
SHP-2—Ac-FYDIDpYAA-NH2500.066750pH 7.4Open
SHP-2—Ac-SASASpYDWEF-NH2350.18190pH 7.4Open
SHP-2—Ac-SASASpYSASA-NH2422.318pH 7.4Open
SHP-2—Ac-WAGDDpYAA-NH2360.068530pH 7.4Open
SHP-2—Ac-WDEDFpYAA-NH2480.0431.1 × 10³pH 7.4Open
SHP-2—Ac-WDEDFpYDWEF-NH2430.00636.8 × 10³pH 7.4Open
SHP-2—Ac-WDEDFpYRWKF-NH2730.21340pH 7.4Open
SHP-2—Ac-WDEDFpYSASA-NH2500.0461.1 × 10³pH 7.4Open
SHP-2—Ac-WRKRFpYDWEF-NH21.30.562.3pH 7.4Open