Values CatLog read from this paper
A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin
PMID 14747460doi:10.1074/jbc.m400666200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) from Treponema pallidum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6α-(1-hydroxy-1-methylethyl)penicillanate | 8 | 0.0208 | 380 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6α-(1-hydroxy-1-methylethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6α-(1-hydroxyethyl)penicillanate | 11.5 | 0.0033 | 3.5 × 10³ | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6α-(1-hydroxyethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6α-(hydroxymethyl)penicillanate | 11.5 | 0.0013 | 8.9 × 10³ | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6α-(hydroxymethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6β-(1-hydroxy-1-methylethyl)penicillanate | 17 | 0.0286 | 590 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6β-(1-hydroxy-1-methylethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6β-(1-hydroxyethyl)penicillanate | 10.8 | 0.0039 | 2.8 × 10³ | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6β-(1-hydroxyethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | 6β-(hydroxymethyl)penicillanate | 10.6 | 0.0025 | 4.2 × 10³ | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), 6β-(hydroxymethyl)penicillanate |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | Ampicillin | 6.8 | 0.0121 | 560 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), Ampicillin |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | BOCILLIN FL | 5 | 0.0069 | 720 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), BOCILLIN FL |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | Carbenicillin | 11.7 | 0.0195 | 600 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), Carbenicillin |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | Cloxacillin | 5 | 0.0967 | 50 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), Cloxacillin |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | Oxacillin | 3.7 | 0.0955 | 40 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), Oxacillin |
| Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity) | Treponema pallidum | Penicillin G | 5.9 | 0.0364 | 160 | pH 7.4 | Open record: Tp47 (47-kDa membrane lipoprotein, penicillin-binding protein with beta-lactamase activity), Penicillin G |