Values CatLog read from this paper
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
PMID 25697095doi:10.1042/bj20141159Open in Browse
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CatLog read 7 records (17 values) from this paper: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | Coenzyme Q1 | 0.19 | 0.124 | 1.5 | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), Coenzyme Q1 |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | Duroquinone | 0.27 | 0.143 | 1.9 | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), Duroquinone |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | L-proline | — | — | 7.5 × 10⁻⁵ | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), L-proline |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | Menadione | 0.28 | 0.025 | 11 | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), Menadione |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | trans-4-hydroxy-L-proline200 μM CoQ1 as terminal electron acceptor | 0.19 | 200 | 9.3 × 10⁻⁴ | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), trans-4-hydroxy-L-proline |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | trans-4-hydroxy-L-prolineo-aminobenzaldehyde assay (443 nm) | 0.002 | 28 | 7 × 10⁻⁵ | pH 7.5, 25 °C | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), trans-4-hydroxy-L-proline |
| proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH) | Homo sapiens | trans-4-hydroxy-L-proline | 0.22 | — | — | pH 7.5 | Open record: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH), trans-4-hydroxy-L-proline |