CatLogenzyme kinetics catalog

EC 1.5.5.2: proline dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 7 records for EC 1.5.5.2 from 1 paper, for 1 organism. Names in these papers: proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 44 records for EC 1.5.5.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.5.5.2 in Browse.

Papers

PaperOrganismsRecords
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluriaHomo sapiens7

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapiensCoenzyme Q10.190.1241.5pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapiensDuroquinone0.270.1431.9pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapiensL-proline——7.5 × 10⁻⁵pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapiensMenadione0.280.02511pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapienstrans-4-hydroxy-L-proline200 μM CoQ1 as terminal electron acceptor0.192009.3 × 10⁻⁴pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapienstrans-4-hydroxy-L-prolineo-aminobenzaldehyde assay (443 nm)0.002287 × 10⁻⁵pH 7.5, 25 °CPMID 25697095Open
proline dehydrogenase 2 (PRODH2; hydroxyproline dehydrogenase, HYPDH)Homo sapienstrans-4-hydroxy-L-proline0.22——pH 7.5PMID 25697095Open