Values CatLog read from this paper
The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions
PMID 14583605doi:10.1074/jbc.m309691200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 53 records (73 values) from this paper: activated factor X (FXa), FVIIIa·FIXa, RVV-X and 1 more from Homo sapiens, Russell's viper.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 20 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| activated factor X (FXa) | Homo sapiens | benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | 211 | 0.318 | 664 calc. | Open record: activated factor X (FXa), benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa) | Homo sapiens | benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | 254 | 0.061 | 4.2 × 10³ calc. | Open record: activated factor X (FXa), benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 3.6 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 12 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 17 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 30 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 15 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 15 | Open record: activated factor X (FXa), ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa) | Homo sapiens | prothrombinno FVa; 0.2 nM FXa | 0.0065 | 3.06 × 10⁻⁴ | 21 calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa), prothrombin |
| activated factor X (FXa) | Homo sapiens | prothrombin0.1 nM FXa | 5.7 | 8.6 × 10⁻⁵ | 6.6 × 10⁴ calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa), prothrombin |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | 196 | 0.339 | 578 calc. | Open record: activated factor X (FXa) variant E36K/E37K/E39K, benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | 215 | 0.059 | 3.6 × 10³ calc. | Open record: activated factor X (FXa) variant E36K/E37K/E39K, benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 7.6 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 22 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 36 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 26 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 19 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 23 | Open record: activated factor X (FXa) variant E36K/E37K/E39K, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | prothrombinno FVa; 0.2 nM FXa | 6.9 × 10⁻⁴ | 2.99 × 10⁻⁴ | 2.3 calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E36K/E37K/E39K, prothrombin |
| activated factor X (FXa)variant E36K/E37K/E39K | Homo sapiens | prothrombin0.1 nM FXa | 0.6 | 4.5 × 10⁻⁵ | 1.3 × 10⁴ calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E36K/E37K/E39K, prothrombin |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | 200 | 0.333 | 600 calc. | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | 214 | 0.052 | 4.1 × 10³ calc. | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 7.6 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ile-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 19 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Ala-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 21 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Glu-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 27 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Leu-Thr-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 17 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Ser-Val-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | — | — | 19 | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, ortho-aminobenzoyl-Val-Gln-Phe-Arg-Thr-Leu-Gly-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine | |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | prothrombinno FVa; 0.2 nM FXa | 7.4 × 10⁻⁴ | 2.93 × 10⁻⁴ | 2.5 calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, prothrombin |
| activated factor X (FXa)variant E36Q/E37Q/E39Q | Homo sapiens | prothrombin0.1 nM FXa | 0.6 | 5.7 × 10⁻⁵ | 1.1 × 10⁴ calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E36Q/E37Q/E39Q, prothrombin |
| activated factor X (FXa)variant E74K/E76K/E77K | Homo sapiens | benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | 139 | 0.739 | 188 calc. | Open record: activated factor X (FXa) variant E74K/E76K/E77K, benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E74K/E76K/E77K | Homo sapiens | benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | 269 | 0.112 | 2.40 × 10³ calc. | Open record: activated factor X (FXa) variant E74K/E76K/E77K, benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E74K/E76K/E77K | Homo sapiens | prothrombinno FVa; 0.2 nM FXa | 0.0053 | 5.19 × 10⁻⁴ | 10 calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E74K/E76K/E77K, prothrombin |
| activated factor X (FXa)variant E74K/E76K/E77K | Homo sapiens | prothrombin0.1 nM FXa | 7.3 | 1.11 × 10⁻⁴ | 6.6 × 10⁴ calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E74K/E76K/E77K, prothrombin |
| activated factor X (FXa)variant E74Q/E76Q/E77Q | Homo sapiens | benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | 148 | 0.529 | 280 calc. | Open record: activated factor X (FXa) variant E74Q/E76Q/E77Q, benzyl-Ile-Glu-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E74Q/E76Q/E77Q | Homo sapiens | benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | 270 | 0.094 | 2.9 × 10³ calc. | Open record: activated factor X (FXa) variant E74Q/E76Q/E77Q, benzyloxycarbonyl-D-Arg-Gly-Arg-p-nitroanilide | |
| activated factor X (FXa)variant E74Q/E76Q/E77Q | Homo sapiens | prothrombinno FVa; 0.2 nM FXa | 0.0045 | 1.81 × 10⁻⁴ | 25 calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E74Q/E76Q/E77Q, prothrombin |
| activated factor X (FXa)variant E74Q/E76Q/E77Q | Homo sapiens | prothrombin0.1 nM FXa | 10.5 | 1.29 × 10⁻⁴ | 8.14 × 10⁴ calc. | pH 7.4, 25 °C | Open record: activated factor X (FXa) variant E74Q/E76Q/E77Q, prothrombin |
| FVIIIa·FIXa | Homo sapiens | coagulation factor X | — | — | 1.11 × 10⁵ | pH 7.4, 25 °C | Open record: FVIIIa·FIXa, coagulation factor X |
| FVIIIa·FIXa | Homo sapiens | coagulation factor X | — | — | 1.14 × 10⁵ | pH 7.4, 25 °C | Open record: FVIIIa·FIXa, coagulation factor X |
| FVIIIa·FIXa | Homo sapiens | coagulation factor X | — | — | 7.3 × 10⁴ | pH 7.4, 25 °C | Open record: FVIIIa·FIXa, coagulation factor X |
| FVIIIa·FIXa | Homo sapiens | coagulation factor X | — | — | 1.28 × 10⁵ | pH 7.4, 25 °C | Open record: FVIIIa·FIXa, coagulation factor X |
| FVIIIa·FIXa | Homo sapiens | coagulation factor X | — | — | 5.1 × 10⁴ | pH 7.4, 25 °C | Open record: FVIIIa·FIXa, coagulation factor X |
| RVV-X | Russell's viper | coagulation factor X | — | — | 250 | pH 7.4, 25 °C | Open record: RVV-X, coagulation factor X |
| RVV-X | Russell's viper | coagulation factor X | — | — | 230 | pH 7.4, 25 °C | Open record: RVV-X, coagulation factor X |
| RVV-X | Russell's viper | coagulation factor Xlike another record | — | — | 270 | pH 7.4, 25 °C | Open record: RVV-X, coagulation factor X |
| RVV-X | Russell's viper | coagulation factor X | — | — | 300 | pH 7.4, 25 °C | Open record: RVV-X, coagulation factor X |
| RVV-X | Russell's viper | coagulation factor Xlike another record | — | — | 270 | pH 7.4, 25 °C | Open record: RVV-X, coagulation factor X |
| TF·FVIIa | Homo sapiens | coagulation factor X | — | — | 2 × 10⁴ | pH 7.4, 25 °C | Open record: TF·FVIIa, coagulation factor X |
| TF·FVIIa | Homo sapiens | coagulation factor X | — | — | 2.4 × 10⁴ | pH 7.4, 25 °C | Open record: TF·FVIIa, coagulation factor X |
| TF·FVIIa | Homo sapiens | coagulation factor X | — | — | 1.2 × 10⁴ | pH 7.4, 25 °C | Open record: TF·FVIIa, coagulation factor X |
| TF·FVIIa | Homo sapiens | coagulation factor X | — | — | 2.2 × 10⁴ | pH 7.4, 25 °C | Open record: TF·FVIIa, coagulation factor X |
| TF·FVIIa | Homo sapiens | coagulation factor X | — | — | 2.9 × 10⁴ | pH 7.4, 25 °C | Open record: TF·FVIIa, coagulation factor X |