Values CatLog read from this paper
Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2
PMID 17181551doi:10.1111/j.1471-4159.2006.04290.xOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (12 values) from this paper: tryptophan hydroxylase 2 (TPH2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| tryptophan hydroxylase 2 (TPH2) | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | — | 0.0217 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2), (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2) | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterinTEV-cleaved TPH2 (fusion partner removed) | — | 0.0684 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2), (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2) | Homo sapiens | L-tryptophan | — | 0.0282 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2), L-tryptophan |
| tryptophan hydroxylase 2 (TPH2) | Homo sapiens | L-tryptophanTEV-cleaved TPH2 (fusion partner removed) | — | 0.0413 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2), L-tryptophan |
| tryptophan hydroxylase 2 (TPH2)variant P449R | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | — | 0.0147 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant P449R, (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2)variant P449R | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterinTEV-cleaved TPH2 (fusion partner removed) | — | 0.0518 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant P449R, (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2)variant P449R | Homo sapiens | L-tryptophan | — | 0.0255 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant P449R, L-tryptophan |
| tryptophan hydroxylase 2 (TPH2)variant P449R | Homo sapiens | L-tryptophanTEV-cleaved TPH2 (fusion partner removed) | — | 0.0511 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant P449R, L-tryptophan |
| tryptophan hydroxylase 2 (TPH2)variant R441H | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin | — | 0.0149 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant R441H, (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2)variant R441H | Homo sapiens | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterinTEV-cleaved TPH2 (fusion partner removed) | — | 0.0289 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant R441H, (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin |
| tryptophan hydroxylase 2 (TPH2)variant R441H | Homo sapiens | L-tryptophan | — | 0.0186 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant R441H, L-tryptophan |
| tryptophan hydroxylase 2 (TPH2)variant R441H | Homo sapiens | L-tryptophanTEV-cleaved TPH2 (fusion partner removed) | — | 0.0334 | — | pH 7, 30 °C | Open record: tryptophan hydroxylase 2 (TPH2) variant R441H, L-tryptophan |