Values CatLog read from this paper

Role of residues 104, 164, 166, 238 and 240 in the substrate profile of PER-1 beta-lactamase hydrolysing third-generation cephalosporins

PMID 9494118doi:10.1042/bj3301443Open in Browse

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CatLog read 44 records (132 values) from this paper: PER-1 β-lactamase from Pseudomonas aeruginosa.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.5.2.6

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
PER-1 β-lactamase	Pseudomonas aeruginosa	Aztreonam	4.3	0.0442	97.3	pH 7, 30 °C	Open record: PER-1 β-lactamase, Aztreonam
PER-1 β-lactamase	Pseudomonas aeruginosa	Cefotaxime	43	0.652	66	pH 7, 30 °C	Open record: PER-1 β-lactamase, Cefotaxime
PER-1 β-lactamase	Pseudomonas aeruginosa	Ceftazidime	70	3.519	19.9	pH 7, 30 °C	Open record: PER-1 β-lactamase, Ceftazidime
PER-1 β-lactamase	Pseudomonas aeruginosa	Cephaloridine	13	0.237	55	pH 7, 30 °C	Open record: PER-1 β-lactamase, Cephaloridine
PER-1 β-lactamase	Pseudomonas aeruginosa	Cephalothin	12.4	0.046	269	pH 7, 30 °C	Open record: PER-1 β-lactamase, Cephalothin
PER-1 β-lactamase	Pseudomonas aeruginosa	Penicillin G	7.2	0.0313	230	pH 7, 30 °C	Open record: PER-1 β-lactamase, Penicillin G
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Aztreonam	2.2	0.035	62.8	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Aztreonam
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Cefotaxime	16.8	0.306	55	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Cefotaxime
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Ceftazidime	37	2.213	16.7	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Ceftazidime
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Cephaloridine	6	0.151	39.7	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Cephaloridine
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Cephalothin	6.1	0.0415	147	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Cephalothin
PER-1 β-lactamasevariant A164S	Pseudomonas aeruginosa	Penicillin G	3.2	0.03	106	pH 7, 30 °C	Open record: PER-1 β-lactamase variant A164S, Penicillin G
PER-1 β-lactamasevariant E166A	Pseudomonas aeruginosa	Aztreonam	0.5	0.171	2.9	pH 7, 30 °C	Open record: PER-1 β-lactamase variant E166A, Aztreonam
PER-1 β-lactamasevariant E166A	Pseudomonas aeruginosa	Ceftazidime	1.1	0.609	1.8	pH 7, 30 °C	Open record: PER-1 β-lactamase variant E166A, Ceftazidime
PER-1 β-lactamasevariant E166A	Pseudomonas aeruginosa	Cephaloridine	0.1	0.04	2.5	pH 7, 30 °C	Open record: PER-1 β-lactamase variant E166A, Cephaloridine
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Aztreonam	6.3	0.17	37	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Aztreonam
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Cefotaxime	24.5	0.499	49	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Cefotaxime
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Ceftazidime	24.8	3.007	8.2	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Ceftazidime
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Cephaloridine	9.3	0.12	77.5	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Cephaloridine
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Cephalothin	6.7	0.0217	309	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Cephalothin
PER-1 β-lactamasevariant G240E	Pseudomonas aeruginosa	Penicillin G	7	0.028	250	pH 7, 30 °C	Open record: PER-1 β-lactamase variant G240E, Penicillin G
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Aztreonam	1.7	0.014	121.4	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Aztreonam
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Cefotaxime	5.6	0.101	55.4	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Cefotaxime
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Ceftazidime	25.1	1.811	13.8	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Ceftazidime
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Cephaloridine	19.5	0.599	32.5	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Cephaloridine
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Cephalothin	18	0.147	122	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Cephalothin
PER-1 β-lactamasevariant N104G	Pseudomonas aeruginosa	Penicillin G	0.7	0.0053	132	pH 7, 30 °C	Open record: PER-1 β-lactamase variant N104G, Penicillin G
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Aztreonam	5.9	0.0161	366	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Aztreonam
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Cefotaxime	70	1.22	57.4	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Cefotaxime
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Ceftazidime	148	7.673	19.3	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Ceftazidime
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Cephaloridine	10	0.259	38	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Cephaloridine
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Cephalothin	12	0.062	193.5	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Cephalothin
PER-1 β-lactamasevariant Q104G	Pseudomonas aeruginosa	Penicillin G	7	0.0415	168	pH 7, 30 °C	Open record: PER-1 β-lactamase variant Q104G, Penicillin G
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Aztreonam	2.9	0.021	138	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Aztreonam
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Cefotaxime	46.2	0.88	52.5	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Cefotaxime
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Ceftazidime	76.8	5.604	13.7	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Ceftazidime
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Cephaloridine	4.5	0.124	36.3	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Cephaloridine
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Cephalothin	11.6	0.083	140	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Cephalothin
PER-1 β-lactamasevariant S238G	Pseudomonas aeruginosa	Penicillin G	3.5	0.0077	454	pH 7, 30 °C	Open record: PER-1 β-lactamase variant S238G, Penicillin G
PER-1 β-lactamasevariant T104E	Pseudomonas aeruginosa	Aztreonam	0.1	0.032	3.1	pH 7, 30 °C	Open record: PER-1 β-lactamase variant T104E, Aztreonam
PER-1 β-lactamasevariant T104E	Pseudomonas aeruginosa	Cefotaxime	0.06	0.448	0.13	pH 7, 30 °C	Open record: PER-1 β-lactamase variant T104E, Cefotaxime
PER-1 β-lactamasevariant T104E	Pseudomonas aeruginosa	Ceftazidime	0.16	0.121	1.3	pH 7, 30 °C	Open record: PER-1 β-lactamase variant T104E, Ceftazidime
PER-1 β-lactamasevariant T104E	Pseudomonas aeruginosa	Cephaloridine	0.14	0.0025	56	pH 7, 30 °C	Open record: PER-1 β-lactamase variant T104E, Cephaloridine
PER-1 β-lactamasevariant T104E	Pseudomonas aeruginosa	Cephalothin	0.44	0.003	146	pH 7, 30 °C	Open record: PER-1 β-lactamase variant T104E, Cephalothin