Values CatLog read from this paper
Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine
PMID 9692994doi:10.1021/bi980475rOpen in Browse
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CatLog read 13 records (31 values) from this paper: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) from Rattus norvegicus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) | Rattus norvegicus | 9,10-phenanthrenequinone | 2.85 | 0.002 | 1.43 × 10³ | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9), 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) | Rattus norvegicus | 9,10-phenanthrenequinone | 1.83 | — | 1.9 × 10³ | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9), 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50E | Rattus norvegicus | 9,10-phenanthrenequinone | 0.015 | 0.012 | 1.3 | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50E, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50N | Rattus norvegicus | 9,10-phenanthrenequinone | 0.012 | 0.056 | 0.17 | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50N, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50N | Rattus norvegicus | 9,10-phenanthrenequinone | 0.55 | — | 18 | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50N, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant H117A | Rattus norvegicus | 9,10-phenanthrenequinone | 0.038 | 0.044 | 0.83 | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant H117A, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant H117A | Rattus norvegicus | 9,10-phenanthrenequinone | 0.217 | — | 5 | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant H117A, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant K84M | Rattus norvegicus | 9,10-phenanthrenequinone | 0.0067 | — | — | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant K84M, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant K84R | Rattus norvegicus | 9,10-phenanthrenequinone | 0.055 | — | 0.83 | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant K84R, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55F | Rattus norvegicus | 9,10-phenanthrenequinone | 1.45 | 0.014 | 103 | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55F, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55F | Rattus norvegicus | 9,10-phenanthrenequinone | 1.28 | — | 122 | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55F, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55S | Rattus norvegicus | 9,10-phenanthrenequinone | 1.45 | 0.026 | 55 | pH 6, 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55S, 9,10-phenanthrenequinone |
| 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55S | Rattus norvegicus | 9,10-phenanthrenequinone | 2.17 | — | 167 | 25 °C | Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55S, 9,10-phenanthrenequinone |