EC 1.1.1.213: 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)

OxidoreductasesOpen in Browse

CatLog read 176 records for EC 1.1.1.213 from 7 papers, for 3 organisms. Names in these papers: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), dihydrodiol dehydrogenase DD4 (pI 5.4), NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), dihydrodiol dehydrogenase DD2 (pI 7.6) and 8 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 56 records for EC 1.1.1.213 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.213 in Browse.

Papers

Papers with records for EC 1.1.1.213
Paper	Organisms	Records
Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): a member of the aldo-keto reductase family highly expressed in kidney cytosol	Rattus norvegicus	51
Structural and functional comparison of two human liver dihydrodiol dehydrogenases associated with 3 alpha-hydroxysteroid dehydrogenase activity	Homo sapiens	40
Demonstration of 3 alpha(17 beta)-hydroxysteroid dehydrogenase distinct from 3 alpha-hydroxysteroid dehydrogenase in hamster liver	Mesocricetus auratus	32
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and…	Homo sapiens	26
Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine	Rattus norvegicus	13
Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular…	Homo sapiens	11
Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution	Homo sapiens	3

Records

Records for EC 1.1.1.213 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)	Rattus norvegicus	9,10-phenanthrenequinone	2.85	0.002	1.43 × 10³	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9), 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)	Rattus norvegicus	9,10-phenanthrenequinone	1.83	—	1.9 × 10³	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9), 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50E	Rattus norvegicus	9,10-phenanthrenequinone	0.015	0.012	1.3	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50E, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50N	Rattus norvegicus	9,10-phenanthrenequinone	0.012	0.056	0.17	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50N, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant D50N	Rattus norvegicus	9,10-phenanthrenequinone	0.55	—	18	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant D50N, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant H117A	Rattus norvegicus	9,10-phenanthrenequinone	0.038	0.044	0.83	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant H117A, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant H117A	Rattus norvegicus	9,10-phenanthrenequinone	0.217	—	5	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant H117A, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant K84M	Rattus norvegicus	9,10-phenanthrenequinone	0.0067	—	—	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant K84M, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant K84R	Rattus norvegicus	9,10-phenanthrenequinone	0.055	—	0.83	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant K84R, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55F	Rattus norvegicus	9,10-phenanthrenequinone	1.45	0.014	103	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55F, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55F	Rattus norvegicus	9,10-phenanthrenequinone	1.28	—	122	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55F, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55S	Rattus norvegicus	9,10-phenanthrenequinone	1.45	0.026	55	pH 6, 25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55S, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9)variant Y55S	Rattus norvegicus	9,10-phenanthrenequinone	2.17	—	167	25 °C	PMID 9692994	Open record: 3α-hydroxysteroid dehydrogenase (3α-HSD, AKR1C9) variant Y55S, 9,10-phenanthrenequinone
3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)	Homo sapiens	5α-dihydrotestosterone	0.025	0.0011	22	pH 7.5, 37 °C	PMID 11514561	Open record: 3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), 5α-dihydrotestosterone
3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)	Homo sapiens	androst-4-ene-3,17-dione	0.00112	0.00138	0.82	pH 7.5, 37 °C	PMID 11514561	Open record: 3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), androst-4-ene-3,17-dione
3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2)	Homo sapiens	testosterone	1.18 × 10⁻⁴	6.7 × 10⁻⁴	0.18	pH 7.5, 37 °C	PMID 11514561	Open record: 3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3, AKR1C2), testosterone
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	0.011	0.0806	0.13	pH 7, 37 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 17β-hydroxy-5α-androstan-3-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	4.3 × 10⁻⁴	0.0317	0.013	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 17β-hydroxy-5α-androstan-3-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	20α-hydroxy-5β-pregnan-3-one	0.0538	0.0194	2.78	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 20α-hydroxy-5β-pregnan-3-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	20α-hydroxyprogesterone	0.02	0.0147	1.37	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 20α-hydroxyprogesterone
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	3α-hydroxy-5α-androstan-17-onespectrophotometric assay (NADPH formation at 340 nm)	0.001	0.0417	0.023	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 3α-hydroxy-5α-androstan-17-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	3α-hydroxy-5α-androstan-17-onespectrophotometric assay (NADPH absorbance change at 340 nm)	0.003	0.021	0.15	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 3α-hydroxy-5α-androstan-17-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	3β-hydroxy-5β-pregnan-20-one	0.0183	0.0162	1.13	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 3β-hydroxy-5β-pregnan-20-one
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	5α-androstane-3,17-dione	0.0078	0.00677	1.2	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), 5α-androstane-3,17-dione
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	progesterone	0.0048	0.00265	1.82	pH 7, 25 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), progesterone
AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1)	Homo sapiens	testosterone	7.3 × 10⁻⁴	0.0398	0.018	pH 7, 37 °C	PMID 10998348	Open record: AKR1C1 (20α(3α)-HSD, dihydrodiol dehydrogenase 1), testosterone
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	4-Androsten-3α-ol-17-one	0.18	3 × 10⁻⁴	600	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 4-Androsten-3α-ol-17-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	4-Androstene-3α,17β-diol	0.127	0.0019	67	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 4-Androstene-3α,17β-diol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	4-Pregnen-3α-ol-20-one	0.133	7 × 10⁻⁴	180	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 4-Pregnen-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5α-Androstan-3α-ol-17-one	0.0123	0.0039	3.2	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5α-Androstan-3α-ol-17-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5α-Androstane-3α,17β-diol	0.0035	0.0038	1	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5α-Androstane-3α,17β-diol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5α-Pregnan-3α-ol-20-one	0.0018	0.0012	1.5	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5α-Pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5α-Pregnane-3α,20α-diol	0.0038	0.0019	2	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5α-Pregnane-3α,20α-diol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-Androstan-3α-ol-17-one	0.028	7 × 10⁻⁴	40	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-Androstan-3α-ol-17-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-androstane-3,17-dione	0.047	0.0021	22 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-androstane-3,17-dione
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-Androstane-3α,17β-diol	0.0132	0.001	13.2	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-Androstane-3α,17β-diol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-pregnan-20α-ol-3-one	0.115	0.0027	43 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-pregnan-20α-ol-3-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-Pregnan-3α-ol-20-one	0.08	3 × 10⁻⁴	270	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-Pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NAD+; cosubstrate NAD+	—	3 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NADP+; cosubstrate NADP+	—	0.0025	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-pregnane-3,20-dione	0.105	0.0024	44 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-pregnane-3,20-dione
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	5β-Pregnane-3α,20α-diol	0.132	5 × 10⁻⁴	270	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 5β-Pregnane-3α,20α-diol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione	0.1	0.023	4.3 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	9,10-phenanthrenequinone	0.18	0.038	4.8 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), 9,10-phenanthrenequinone
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Chenodeoxycholic acid	0.068	0.0012	57	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Chenodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Cholic acid	0.038	0.015	2.5	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Cholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	cis-benzene dihydrodiol	0.043	2.5	0.017 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), cis-benzene dihydrodiol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	dehydrolithocholic acid	0.022	4 × 10⁻⁴	54 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), dehydrolithocholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Deoxycholic acid	0.0145	0.0014	10.3	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Deoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	diacetyl	0.17	0.42	0.40 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), diacetyl
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Glycochenodeoxycholic acid	0.102	0.001	102	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Glycochenodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Glycolithocholic acid	0.063	2 × 10⁻⁴	320	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Glycolithocholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Glycoursodeoxycholic acid	0.118	0.0013	92	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Glycoursodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Hyodeoxycholic acid	0.002	0.0017	1.2	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Hyodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	isatin	0.28	0.022	13 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), isatin
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Lithocholic acid	0.032	3 × 10⁻⁴	105	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Lithocholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Murocholic acid	0.0035	0.0034	1	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Murocholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	NAD+	0.065	0.08	0.82	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), NAD+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	NADP+	0.042	1.1	0.038	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), NADP+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	S-tetralol	0.017	1.7	0.0098 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), S-tetralol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Taurolithocholic acid	0.085	3 × 10⁻⁴	280	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Taurolithocholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Tauroursodeoxycholic acid	0.132	0.001	132	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Tauroursodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	trans-benzene dihydrodiol	0.0098	0.79	0.012 calc.	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), trans-benzene dihydrodiol
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	Ursodeoxycholic acid	0.085	3 × 10⁻⁴	280	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), Ursodeoxycholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)	Rattus norvegicus	β-Muricholic acid	0.0097	0.0058	1.7	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd), β-Muricholic acid
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant E276R	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NAD+; cosubstrate NAD+	—	0.0028	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant E276R, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant E276R	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NADP+; cosubstrate NADP+	—	4 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant E276R, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant E276R	Rattus norvegicus	NAD+	0.047	1.1	0.042	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant E276R, NAD+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant E276R	Rattus norvegicus	NADP+	0.058	0.022	2.65	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant E276R, NADP+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NAD+; cosubstrate NAD+	—	0.0028	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NADP+; cosubstrate NADP+	—	5 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K	Rattus norvegicus	NAD+	0.07	0.3	0.23	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K, NAD+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K	Rattus norvegicus	NADP+	0.052	0.2	0.27	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K, NADP+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K/E276R	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NAD+; cosubstrate NAD+	—	0.001	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K/E276R, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K/E276R	Rattus norvegicus	5β-pregnan-3α-ol-20-oneTHP varied with 1 mM NADP+; cosubstrate NADP+	—	1 × 10⁻⁴	—	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K/E276R, 5β-pregnan-3α-ol-20-one
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K/E276R	Rattus norvegicus	NAD+	0.108	1.1	0.098	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K/E276R, NAD+
AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd)variant Q270K/E276R	Rattus norvegicus	NADP+	0.02	0.003	6.7	pH 7.4, 25 °C	PMID 17475203	Open record: AKR1C17 (NAD+-dependent 3α-hydroxysteroid dehydrogenase, RAKd) variant Q270K/E276R, NADP+
AKR1C2 (type 3 3α-HSD, bile-acid binding protein)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	0.0038	0.026	0.15	pH 7, 37 °C	PMID 10998348	Open record: AKR1C2 (type 3 3α-HSD, bile-acid binding protein), 17β-hydroxy-5α-androstan-3-one
AKR1C2 (type 3 3α-HSD, bile-acid binding protein)	Homo sapiens	3α-hydroxy-5α-androstan-17-one	0.007	0.00973	0.72	pH 7, 25 °C	PMID 10998348	Open record: AKR1C2 (type 3 3α-HSD, bile-acid binding protein), 3α-hydroxy-5α-androstan-17-one
AKR1C2 (type 3 3α-HSD, bile-acid binding protein)	Homo sapiens	5α-androstane-3,17-dione	0.0232	0.00626	3.7	pH 7, 25 °C	PMID 10998348	Open record: AKR1C2 (type 3 3α-HSD, bile-acid binding protein), 5α-androstane-3,17-dione
AKR1C2 (type 3 3α-HSD, bile-acid binding protein)	Homo sapiens	5α-androstane-3α,17β-diol	0.004	0.022	0.18	pH 7, 25 °C	PMID 10998348	Open record: AKR1C2 (type 3 3α-HSD, bile-acid binding protein), 5α-androstane-3α,17β-diol
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	0.0042	—	0.1	pH 7, 37 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 17β-hydroxy-5α-androstan-3-one
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	17β-hydroxy-5α-androstan-3-onespectrophotometric assay (NADPH absorbance change at 340 nm)	0.0043	0.0198	0.22	pH 7, 25 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 17β-hydroxy-5α-androstan-3-one
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	17β-hydroxy-5α-androstan-3-onespectrophotometric assay (NADPH formation at 340 nm)	7.7 × 10⁻⁴	0.0119	0.063	pH 7, 25 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 17β-hydroxy-5α-androstan-3-one
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	3α-hydroxy-5α-androstan-17-one	0.0062	0.00896	0.7	pH 7, 25 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 3α-hydroxy-5α-androstan-17-one
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	5α-androstane-3,17-dione	0.0047	0.005	0.93	pH 7, 25 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 5α-androstane-3,17-dione
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	5α-androstane-3α,17β-diol	0.0025	0.0272	0.1	pH 7, 25 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), 5α-androstane-3α,17β-diol
AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD)	Homo sapiens	testosterone	8.2 × 10⁻⁴	0.0243	0.033	pH 7, 37 °C	PMID 10998348	Open record: AKR1C3 (type 2 3α(17β)-HSD, type 5 17β-HSD), testosterone
AKR1C4 (type 1 3α-HSD, chlordecone reductase)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	0.032	0.0083	3.85	pH 7, 37 °C	PMID 10998348	Open record: AKR1C4 (type 1 3α-HSD, chlordecone reductase), 17β-hydroxy-5α-androstan-3-one
AKR1C4 (type 1 3α-HSD, chlordecone reductase)	Homo sapiens	17β-hydroxy-5α-androstan-3-one	0.0332	0.0034	9.77	pH 7, 25 °C	PMID 10998348	Open record: AKR1C4 (type 1 3α-HSD, chlordecone reductase), 17β-hydroxy-5α-androstan-3-one
AKR1C4 (type 1 3α-HSD, chlordecone reductase)	Homo sapiens	3α-hydroxy-5α-androstan-17-one	0.0232	0.00504	4.6	pH 7, 25 °C	PMID 10998348	Open record: AKR1C4 (type 1 3α-HSD, chlordecone reductase), 3α-hydroxy-5α-androstan-17-one
AKR1C4 (type 1 3α-HSD, chlordecone reductase)	Homo sapiens	5α-androstane-3,17-dione	0.0298	0.00144	20.72	pH 7, 25 °C	PMID 10998348	Open record: AKR1C4 (type 1 3α-HSD, chlordecone reductase), 5α-androstane-3,17-dione
AKR1C4 (type 1 3α-HSD, chlordecone reductase)	Homo sapiens	5α-androstane-3α,17β-diol	0.035	0.0105	3.3	pH 7, 25 °C	PMID 10998348	Open record: AKR1C4 (type 1 3α-HSD, chlordecone reductase), 5α-androstane-3α,17β-diol
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	(S)-1,2,3,4-tetrahydronaphthalen-1-ol	0.27	0.26	1.0 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), (S)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	(S)-2,3-dihydro-1H-inden-1-ol	0.158	0.52	0.30 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), (S)-2,3-dihydro-1H-inden-1-ol
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	2-Nitrobenzaldehyde	0.053	6 × 10⁻⁴	89 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 2-Nitrobenzaldehyde
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	3-Nitrobenzaldehyde	0.0155	0.002	7.8 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 3-Nitrobenzaldehyde
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	3α-hydroxy-5α-androstan-17-one	0.0118	0.0078	1.5 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 3α-hydroxy-5α-androstan-17-one
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	5β-Androstane-3,17-dione	0.0103	3 × 10⁻⁴	34 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 5β-Androstane-3,17-dione
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	5β-Pregnane-3,20-dione	0.0098	2 × 10⁻⁴	49 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 5β-Pregnane-3,20-dione
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	5β-Pregnane-3α,20α-diol	0.0037	0.001	3.7 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), 5β-Pregnane-3α,20α-diol
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	Butane-2,3-dione	0.035	0.0033	11 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), Butane-2,3-dione
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	Camphorquinone	0.023	5 × 10⁻⁴	47 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), Camphorquinone
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	Menadione	0.025	0.013	1.9 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), Menadione
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	pyridine-3-carbaldehyde	0.032	0.057	0.56 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), pyridine-3-carbaldehyde
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	trans-1,2-dihydroxy-1,2-dihydronaphthalene	0.028	0.22	0.13 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), trans-1,2-dihydroxy-1,2-dihydronaphthalene
dihydrodiol dehydrogenase DD2 (pI 7.6)	Homo sapiens	trans-cyclohexa-3,5-diene-1,2-diol	0.032	5	0.0063 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD2 (pI 7.6), trans-cyclohexa-3,5-diene-1,2-diol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	(R)-1,2,3,4-tetrahydronaphthalen-1-ol	0.3	0.19	1.6 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), (R)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	(R)-2,3-dihydro-1H-inden-1-ol	0.27	0.3	0.89 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), (R)-2,3-dihydro-1H-inden-1-ol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	(S)-1,2,3,4-tetrahydronaphthalen-1-ol	0.58	0.35	1.7 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), (S)-1,2,3,4-tetrahydronaphthalen-1-ol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	(S)-2,3-dihydro-1H-inden-1-ol	0.32	0.45	0.70 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), (S)-2,3-dihydro-1H-inden-1-ol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	2-Nitrobenzaldehyde	0.18	0.0011	170 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 2-Nitrobenzaldehyde
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	20α-Hydroxy-5β-pregnan-3-one	0.028	6 × 10⁻⁴	47 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 20α-Hydroxy-5β-pregnan-3-one
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3-Nitrobenzaldehyde	0.035	0.017	2.1 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3-Nitrobenzaldehyde
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3-oxo-5β-cholan-24-oic acid	0.0145	1 × 10⁻⁴	140 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3-oxo-5β-cholan-24-oic acid
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3α,7α,12α-trihydroxy-5β-cholan-24-oic acid	0.25	0.024	10 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3α-hydroxy-5α-androstan-17-one	0.09	0.001	90 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3α-hydroxy-5α-androstan-17-one
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3α-Hydroxy-5β-androstan-17-one	0.078	0.0014	56 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3α-Hydroxy-5β-androstan-17-one
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3α-hydroxy-5β-cholan-24-oic acid	0.028	7 × 10⁻⁴	40 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3α-hydroxy-5β-cholan-24-oic acid
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	3α-Hydroxy-5β-pregnan-20-one	0.033	0.0016	21 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 3α-Hydroxy-5β-pregnan-20-one
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	5α-Androstane-3α,17β-diol	0.113	0.0018	63 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 5α-Androstane-3α,17β-diol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	5β-Androstane-3,17-dione	0.08	6 × 10⁻⁴	130 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 5β-Androstane-3,17-dione
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	5β-Androstane-3α,17β-diol	0.127	0.0013	97 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 5β-Androstane-3α,17β-diol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	5β-Pregnane-3,20-dione	0.05	8 × 10⁻⁴	62 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 5β-Pregnane-3,20-dione
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	5β-Pregnane-3α,20α-diol	0.038	2 × 10⁻⁴	190 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), 5β-Pregnane-3α,20α-diol
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	Butane-2,3-dione	0.067	0.0065	10 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), Butane-2,3-dione
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	Camphorquinone	0.135	6 × 10⁻⁴	220 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), Camphorquinone
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	Chenodeoxycholic acid	0.032	0.0011	29 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), Chenodeoxycholic acid
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	cis-1,2-dihydroxycyclohexa-3,5-diene	0.32	1.09	0.29 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), cis-1,2-dihydroxycyclohexa-3,5-diene
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	Deoxycholic acid	0.052	0.0063	8.2 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), Deoxycholic acid
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	pyridine-3-carbaldehyde	0.17	0.33	0.51 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), pyridine-3-carbaldehyde
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	trans-1,2-dihydroxy-1,2-dihydronaphthalene	0.09	0.42	0.21 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), trans-1,2-dihydroxy-1,2-dihydronaphthalene
dihydrodiol dehydrogenase DD4 (pI 5.4)	Homo sapiens	trans-cyclohexa-3,5-diene-1,2-diol	0.037	0.029	1.3 calc.	pH 7.4, 25 °C	PMID 1554355	Open record: dihydrodiol dehydrogenase DD4 (pI 5.4), trans-cyclohexa-3,5-diene-1,2-diol
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	17β-hydroxyandrost-4-en-3-one	0.42	0.0022	190	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 17β-hydroxyandrost-4-en-3-one
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	3α-hydroxy-5β-cholan-24-oic acid	0.05	5 × 10⁻⁴	100	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 3α-hydroxy-5β-cholan-24-oic acid
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5α-Androstane-3α,17β-diol	0.45	0.0031	145	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5α-Androstane-3α,17β-diol
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5α-Pregnane-3α,21-diol-20-one	0.27	0.0025	107	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5α-Pregnane-3α,21-diol-20-one
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Androstan-17β-ol-3-one	0.37	0.0049	75	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Androstan-17β-ol-3-one
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Androstane-3,17-dione	0.17	0.0066	25	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Androstane-3,17-dione
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Androstane-3α,17β-diol	0.85	0.0048	177	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Androstane-3α,17β-diol
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnan-3α-ol-20-one	0.23	0.0046	50	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Pregnan-3α-ol-20-one
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnane-3,20-dione	0.158	0.0038	42	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Pregnane-3,20-dione
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnane-3α,21-diol-20-one	0.37	0.0062	60	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), 5β-Pregnane-3α,21-diol-20-one
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	N-(3α,7α-dihydroxy-5β-cholan-24-oyl)glycine	0.02	0.0075	3.3	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), N-(3α,7α-dihydroxy-5β-cholan-24-oyl)glycine
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	N-(3α-hydroxy-5β-cholan-24-oyl)glycine	0.25	0.003	83	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), N-(3α-hydroxy-5β-cholan-24-oyl)glycine
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	NAD+	—	0.27	—	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), NAD+
NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD)	Mesocricetus auratus	NADH	—	0.02	—	pH 7.5, 25 °C	PMID 2317205	Open record: NAD+-dependent 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+-dependent 3HSD), NADH
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	17α,21-dihydroxy-5β-pregnane-3,11,20-trione	0.43	0.0012	370	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 17α,21-dihydroxy-5β-pregnane-3,11,20-trione
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	3-oxo-5β-cholan-24-oic acid	0.73	0.0015	480	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 3-oxo-5β-cholan-24-oic acid
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	3α-hydroxy-5β-cholan-24-oic acid	0.22	0.004	52	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 3α-hydroxy-5β-cholan-24-oic acid
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5α-Androstan-17β-ol-3-one	0.35	0.0013	270	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5α-Androstan-17β-ol-3-one
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5α-Androstan-3α-ol-17-one	2.72	0.047	58	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5α-Androstan-3α-ol-17-one
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5α-Androstane-3,17-dione	0.57	0.003	180	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5α-Androstane-3,17-dione
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5α-Androstane-3α,17β-diol	1.3	0.015	88	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5α-Androstane-3α,17β-diol
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5α-Pregnan-21-ol-3,20-dione	0.77	0.0057	135	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5α-Pregnan-21-ol-3,20-dione
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Androstan-3α-ol-17-one	1.3	0.012	112	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Androstan-3α-ol-17-one
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Androstane-3,17-dione	0.45	0.001	450	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Androstane-3,17-dione
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Androstane-3α,17β-diol	1.2	0.016	75	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Androstane-3α,17β-diol
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnan-3α-ol-20-one	0.77	0.0039	197	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Pregnan-3α-ol-20-one
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnane-3,20-dione	0.42	8 × 10⁻⁴	520	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Pregnane-3,20-dione
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	5β-Pregnane-3α,21-diol-20-one	0.63	0.0055	115	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), 5β-Pregnane-3α,21-diol-20-one
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	N-(3α,7α-dihydroxy-5β-cholan-24-oyl)glycine	0.2	0.0025	80	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), N-(3α,7α-dihydroxy-5β-cholan-24-oyl)glycine
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	N-(3α-hydroxy-5β-cholan-24-oyl)glycine	0.23	0.0025	93	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), N-(3α-hydroxy-5β-cholan-24-oyl)glycine
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	NADP+	—	0.003	—	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), NADP+
NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD)	Mesocricetus auratus	NADPH	—	0.005	—	pH 7.5, 25 °C	PMID 2317205	Open record: NADP+-dependent 3alpha-hydroxysteroid dehydrogenase (NADP+-dependent 3HSD), NADPH
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	17beta-hydroxy-5alpha-androstan-3-one	0.0018	0.019	0.0965	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 17beta-hydroxy-5alpha-androstan-3-one
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	17beta-hydroxy-5alpha-androstan-3-oneradiometric assay ([14C]-steroid, TLC); NADPH 2.3 mM	0.003	0.0262	0.1145	pH 7, 37 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 17beta-hydroxy-5alpha-androstan-3-one
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	17beta-hydroxy-5alpha-androstan-3-oneradiometric assay (TLC); NADP+ 2.3 mM; cosubstrate NADP+	9.7 × 10⁻⁴	0.0243	0.0398	pH 7, 37 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 17beta-hydroxy-5alpha-androstan-3-one
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	17beta-hydroxyandrost-4-en-3-one	9 × 10⁻⁴	0.0119	0.0757	pH 7, 37 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 17beta-hydroxyandrost-4-en-3-one
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	3alpha-hydroxy-5alpha-androstan-17-one	3.7 × 10⁻⁴	0.0484	0.0078	pH 7, 37 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 3alpha-hydroxy-5alpha-androstan-17-one
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	4-Nitrobenzaldehyde	0.0942	0.0873	1.078	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 4-Nitrobenzaldehyde
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	5alpha-androstane-3,17-dione	0.008	0.00422	1.9	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 5alpha-androstane-3,17-dione
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	5alpha-androstane-3alpha,17beta-diolspectrophotometric assay (A340); NADP+ fixed at 2.3 mM	0.0035	0.0171	0.203	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 5alpha-androstane-3alpha,17beta-diol
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	5alpha-androstane-3alpha,17beta-diolNADP+ 2.3 mM	0.0097	0.0191	0.507	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 5alpha-androstane-3alpha,17beta-diol
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	5alpha-androstane-3alpha,17beta-diol	0.0062	0.0193	0.32	pH 7, 37 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 5alpha-androstane-3alpha,17beta-diol
type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3)	Homo sapiens	9,10-Phenanthrenequinone	0.39	0.0206	18.93	pH 7, 25 °C	PMID 9415401	Open record: type 2 3α-hydroxysteroid dehydrogenase (3α/17β-HSD, AKR1C3), 9,10-Phenanthrenequinone