Values CatLog read from this paper

Critical determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3'-5' exonuclease III

PMID 25748880doi:10.1016/j.bbapap.2015.02.019Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (24 values) from this paper: AP-endonuclease/3'-5' exonuclease III (MtbXthA) from Mycobacterium tuberculosis.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.11.2

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
AP-endonuclease/3'-5' exonuclease III (MtbXthA)	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.012	1.5 × 10⁻⁵	780	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA), 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant D251A	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.002	1.5 × 10⁻⁵	130	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant D251A, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant E57A	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.001	1.6 × 10⁻⁵	60	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant E57A, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant F242S	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.012	1.4 × 10⁻⁵	880	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant F242S, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant W235S	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.012	1.8 × 10⁻⁵	650	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant W235S, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant Y137S	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.008	6.4 × 10⁻⁵	110	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant Y137S, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant Y234S	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.012	2.2 × 10⁻⁵	550	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant Y234S, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)
AP-endonuclease/3'-5' exonuclease III (MtbXthA)variant Y234S/W235S	Mycobacterium tuberculosis	5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)	0.01	1.6 × 10⁻⁵	630	pH 7.8, 37 °C	Open record: AP-endonuclease/3'-5' exonuclease III (MtbXthA) variant Y234S/W235S, 5'-FAM-labelled duplex DNA containing the abasic site analogue tetrahydrofuran (THF)