Values CatLog read from this paper
Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide
PMID 19663506doi:10.1021/bi9007098Open in Browse
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CatLog read 7 records (21 values) from this paper: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1) | Homo sapiens | S-methyl-L-thiocitrulline | 0.0418 | 0.0031 | 13.5 | pH 7.27 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1), S-methyl-L-thiocitrulline |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant E78A | Homo sapiens | N-omega,N-omega-dimethyl-L-arginine | 0.0015 | 13.7 | 1.2 × 10⁻⁴ | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant E78A, N-omega,N-omega-dimethyl-L-arginine | |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant E78A | Homo sapiens | S-methyl-L-thiocitrulline | 0.03 | 0.019 | 1.58 | pH 7.27 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant E78A, S-methyl-L-thiocitrulline |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant L271G | Homo sapiens | N-omega,N-omega-dimethyl-L-arginine | 0.0087 | 0.75 | 0.0115 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant L271G, N-omega,N-omega-dimethyl-L-arginine | |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant L271G | Homo sapiens | S-methyl-L-thiocitrulline | 0.0097 | 0.0014 | 6.8 | pH 7.27 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant L271G, S-methyl-L-thiocitrulline |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant L30A | Homo sapiens | N-omega,N-omega-dimethyl-L-arginine | 0.0168 | 1.4 | 0.012 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant L30A, N-omega,N-omega-dimethyl-L-arginine | |
| DDAH-1 (dimethylarginine dimethylaminohydrolase-1)variant L30A | Homo sapiens | S-methyl-L-thiocitrulline | 0.0418 | 0.0036 | 11.7 | pH 7.27 | Open record: DDAH-1 (dimethylarginine dimethylaminohydrolase-1) variant L30A, S-methyl-L-thiocitrulline |