CatLogenzyme kinetics catalog

Values CatLog read from this paper

Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans

PMID 11172068doi:10.1073/pnas.98.4.2017Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 16 records (26 values) from this paper: choline acetyltransferase (ChAT), 70-kDa isoform from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 8 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.3.1.6

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
choline acetyltransferase (ChAT), 70-kDa isoformHomo sapiensacetyl coenzyme A99.60.02683.72 × 10³pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformHomo sapienscholine—0.478—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant I305THomo sapiensacetyl coenzyme A60.40.0706856 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant I305THomo sapienscholine—0.59—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant L210PHomo sapienscholine352.69313 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant P211AHomo sapiensacetyl coenzyme A418.80.28791455 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant P211AHomo sapienscholine—0.514—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant R420CHomo sapiensacetyl coenzyme A176.80.4618382.9 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant R420CHomo sapienscholine—1.018—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant R482GHomo sapiensacetyl coenzyme A990.09171.1 × 10³ calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant R482GHomo sapienscholine—0.5—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant R560HHomo sapiensacetyl coenzyme A34.10.870839.2 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant S498LHomo sapiensacetyl coenzyme A88.60.0946937 calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant S498LHomo sapienscholine—0.418—pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant V506LHomo sapiensacetyl coenzyme A125.80.06841.84 × 10³ calc.pH 7.4, 37 °COpen
choline acetyltransferase (ChAT), 70-kDa isoformvariant V506LHomo sapienscholine—0.37—pH 7.4, 37 °COpen