Values CatLog read from this paper
Long range communication between exosites 1 and 2 modulates thrombin function
PMID 19589779doi:10.1074/jbc.m109.000042Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: α-thrombin from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| α-thrombin | Homo sapiens | H-D-Phe-Pip-Arg-p-nitroanilideno exosite ligand added | 101.9 | 0.0026 | 3.98 × 10⁴ | Open record: α-thrombin, H-D-Phe-Pip-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | H-D-Phe-Pip-Arg-p-nitroanilidewith 10 μM HD1 (exosite 1-directed DNA aptamer) | 209.4 | 0.0143 | 1.47 × 10⁴ | Open record: α-thrombin, H-D-Phe-Pip-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | H-D-Phe-Pip-Arg-p-nitroanilidewith 10 μM HD22 (exosite 2-directed DNA aptamer) | 106.8 | 0.0121 | 8.8 × 10³ | Open record: α-thrombin, H-D-Phe-Pip-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | H-D-Phe-Pip-Arg-p-nitroanilidewith 10 μM hirudin-(54–65) (exosite 1-directed peptide) | 156.5 | 0.0031 | 5.1 × 10⁴ | Open record: α-thrombin, H-D-Phe-Pip-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | pyro-Glu-Pro-Arg-p-nitroanilideno exosite ligand added | 249.5 | 0.2829 | 900 | Open record: α-thrombin, pyro-Glu-Pro-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | pyro-Glu-Pro-Arg-p-nitroanilidewith 10 μM HD1 (exosite 1-directed DNA aptamer) | 217.1 | 0.195 | 1.1 × 10³ | Open record: α-thrombin, pyro-Glu-Pro-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | pyro-Glu-Pro-Arg-p-nitroanilidewith 10 μM HD22 (exosite 2-directed DNA aptamer) | 231.1 | 0.1554 | 1.5 × 10³ | Open record: α-thrombin, pyro-Glu-Pro-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | pyro-Glu-Pro-Arg-p-nitroanilidewith 10 μM hirudin-(54–65) (exosite 1-directed peptide) | 278.6 | 0.1471 | 1.9 × 10³ | Open record: α-thrombin, pyro-Glu-Pro-Arg-p-nitroanilide | |
| α-thrombin | Homo sapiens | tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate)no exosite ligand added | 234.5 | 0.0164 | 1.43 × 10⁴ | Open record: α-thrombin, tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate) | |
| α-thrombin | Homo sapiens | tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate)with 10 μM HD1 (exosite 1-directed DNA aptamer) | 240.3 | 0.0142 | 1.69 × 10⁴ | Open record: α-thrombin, tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate) | |
| α-thrombin | Homo sapiens | tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate)with 10 μM HD22 (exosite 2-directed DNA aptamer) | 192.8 | 0.0085 | 2.27 × 10⁴ | Open record: α-thrombin, tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate) | |
| α-thrombin | Homo sapiens | tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate)with 10 μM hirudin-(54–65) (exosite 1-directed peptide) | 251.6 | 0.0117 | 2.15 × 10⁴ | Open record: α-thrombin, tosyl-Gly-Pro-Arg-p-nitroanilide (tosyl-Gly-Pro-Arg-p-nitroaniline acetate) |