Values CatLog read from this paper
Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population
PMID 15681899doi:10.2133/dmpk.19.444Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (6 values) from this paper: CYP2B6, CYP1A2 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP1A2 | Homo sapiens | 7-ethoxyresorufin | — | 9.23 × 10⁻⁴ | — | pH 7.4 | Open record: CYP1A2, 7-ethoxyresorufin |
| CYP1A2variant Q478H | Homo sapiens | 7-ethoxyresorufin | — | 8.11 × 10⁻⁴ | — | pH 7.4 | Open record: CYP1A2 variant Q478H, 7-ethoxyresorufin |
| CYP2B6 | Homo sapiens | 7-ethoxy-4-trifluoromethylcoumarin | — | 0.0167 | — | pH 7.6 | Open record: CYP2B6, 7-ethoxy-4-trifluoromethylcoumarin |
| CYP2B6variant P167A | Homo sapiens | 7-ethoxy-4-trifluoromethylcoumarin | — | 0.016 | — | pH 7.6 | Open record: CYP2B6 variant P167A, 7-ethoxy-4-trifluoromethylcoumarin |
| CYP2B6variant Q172H | Homo sapiens | 7-ethoxy-4-trifluoromethylcoumarin | — | 0.0197 | — | pH 7.6 | Open record: CYP2B6 variant Q172H, 7-ethoxy-4-trifluoromethylcoumarin |
| CYP2B6variant R487C | Homo sapiens | 7-ethoxy-4-trifluoromethylcoumarin | — | 0.0182 | — | pH 7.6 | Open record: CYP2B6 variant R487C, 7-ethoxy-4-trifluoromethylcoumarin |