CatLogenzyme kinetics catalog

Values CatLog read from this paper

Biochemical characterization and discovery of inhibitors for PfSir2A: new tricks for an old enzyme

PMID 39897407doi:10.1039/d4cb00206gOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (14 values) from this paper: PfSir2A from Plasmodium falciparum.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) acetylated at Lys9, ARTKQTAR(K-Ac)STGGKAPRKQLASTable 1—0.556—pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) acetylated at Lys9, ARTKQTAR(K-Ac)STGGKAPRKQLASTable 16.4 × 10⁻⁴——pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) acetylated at Lys9, ARTKQTAR(K-Ac)STGGKAPRKQLASwith calf thymus dsDNA 200 ng/uL; Table 1—0.175—pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) acetylated at Lys9, ARTKQTAR(K-Ac)STGGKAPRKQLASwith calf thymus dsDNA 200 ng/uL; Table 18.2 × 10⁻⁴——pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) acetylated at Lys9, ARTKQTAR(K-Ac)STGGKAPRKQLASin the text——0.00115pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) myristoylated at Lys9, ARTKQTAR(K-Myr)STGGKAPRKQLASTable 1—0.0049—pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) myristoylated at Lys9, ARTKQTAR(K-Myr)STGGKAPRKQLASTable 10.0252——pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) myristoylated at Lys9, ARTKQTAR(K-Myr)STGGKAPRKQLASwith calf thymus dsDNA 200 ng/uL; Table 1—9.5 × 10⁻⁴—pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) myristoylated at Lys9, ARTKQTAR(K-Myr)STGGKAPRKQLASwith calf thymus dsDNA 200 ng/uL; Table 10.0305——pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H3 peptide H3(1-22) myristoylated at Lys9, ARTKQTAR(K-Myr)STGGKAPRKQLASin the text——5.14pH 7.5, 37 °COpen
PfSir2APlasmodium falciparumhistone H4 peptide H4(1-19) acetylated at Lys16, SGRGKGGKGLGKGGA(K-Ac)RHR4.3 × 10⁻⁴0.1950.0022 calc.pH 7.5, 37 °COpen
PfSir2APlasmodium falciparump300 peptide p300(1034-1053) acetylated lysine, ERSTELKTEI(K-Ac)EEEDQPSTS0.001140.1020.0112 calc.pH 7.5, 37 °COpen