CatLogenzyme kinetics catalog

Values CatLog read from this paper

Three prime repair exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural, and conformational properties

PMID 38838778doi:10.1016/j.jbc.2024.107438Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (24 values) from this paper: TREX1 (three prime repair exonuclease 1) from Homo sapiens, Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.11.2

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
TREX1 (three prime repair exonuclease 1)Homo sapiens20-mer blunt-ended double-stranded HIV-1 U3 LTR end DNA: 5'-6-fluorescein-AGTGAATTAGCCCTTCCAGT-3' annealed to the complementary 20-mer 5'-ACTGGAAGGGCTAATTCACT-3'9.81.507 × 10⁻⁴6.53 × 10⁴pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Homo sapiens20-mer blunt-ended double-stranded HIV-1 U5 LTR end DNA: 5'-6-fluorescein-TGTGGAAAATCTCTAGCAGT-3' annealed to the complementary 20-mer 5'-ACTGCTAGAGATTTTCCACA-3'10.29.85 × 10⁻⁵1.031 × 10⁵pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Homo sapiens3'-processed double-stranded HIV-1 U3 LTR end DNA with a recessed 3'-end: 18-mer 5'-6-fluorescein-AGTGAATTAGCCCTTCCA-3' (lacking the 3'-GT dinucleotide) annealed to the complementary 20-mer 5'-ACTGGAAGGGCTAATTCACT-3'4.51.604 × 10⁻⁴2.805 × 10⁴pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Homo sapiens3'-processed double-stranded HIV-1 U5 LTR end DNA with a recessed 3'-end: 18-mer 5'-6-fluorescein-TGTGGAAAATCTCTAGCA-3' (lacking the 3'-GT dinucleotide) annealed to the complementary 20-mer 5'-ACTGCTAGAGATTTTCCACA-3'3.85.42 × 10⁻⁵7.02 × 10⁴pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Mus musculus20-mer blunt-ended double-stranded HIV-1 U3 LTR end DNA: 5'-6-fluorescein-AGTGAATTAGCCCTTCCAGT-3' annealed to the complementary 20-mer 5'-ACTGGAAGGGCTAATTCACT-3'12.69.87 × 10⁻⁵1.278 × 10⁵pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Mus musculus20-mer blunt-ended double-stranded HIV-1 U5 LTR end DNA: 5'-6-fluorescein-TGTGGAAAATCTCTAGCAGT-3' annealed to the complementary 20-mer 5'-ACTGCTAGAGATTTTCCACA-3'9.51.095 × 10⁻⁴8.67 × 10⁴pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Mus musculus3'-processed double-stranded HIV-1 U3 LTR end DNA with a recessed 3'-end: 18-mer 5'-6-fluorescein-AGTGAATTAGCCCTTCCA-3' (lacking the 3'-GT dinucleotide) annealed to the complementary 20-mer 5'-ACTGGAAGGGCTAATTCACT-3'6.31.253 × 10⁻⁴5.46 × 10⁴pH 7.5, 37 °COpen
TREX1 (three prime repair exonuclease 1)Mus musculus3'-processed double-stranded HIV-1 U5 LTR end DNA with a recessed 3'-end: 18-mer 5'-6-fluorescein-TGTGGAAAATCTCTAGCA-3' (lacking the 3'-GT dinucleotide) annealed to the complementary 20-mer 5'-ACTGCTAGAGATTTTCCACA-3'4.19.06 × 10⁻⁵4.52 × 10⁴pH 7.5, 37 °COpen