Values CatLog read from this paper

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk

PMID 22942235doi:10.1136/gutjnl-2012-303090Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 14 records (42 values) from this paper: chymotrypsin C from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.2

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
chymotrypsin C	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	15	0.0135	1.1 × 10³	pH 8, 22 °C	Open record: chymotrypsin C, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant A73T	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	16.6	0.0244	680	pH 8, 22 °C	Open record: chymotrypsin C variant A73T, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant D35Y	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	11.7	0.0171	680	pH 8, 22 °C	Open record: chymotrypsin C variant D35Y, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant G18R	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	15.7	0.017	920	pH 8, 22 °C	Open record: chymotrypsin C variant G18R, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant G217S	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	2.7	0.482	5.5	pH 8, 22 °C	Open record: chymotrypsin C variant G217S, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant G32V	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	10	0.59	17	pH 8, 22 °C	Open record: chymotrypsin C variant G32V, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant P249L	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	0.6	0.761	0.79	pH 8, 22 °C	Open record: chymotrypsin C variant P249L, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant Q178R	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	3.5	0.495	7.1	pH 8, 22 °C	Open record: chymotrypsin C variant Q178R, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant Q48R	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	15.1	0.0162	930	pH 8, 22 °C	Open record: chymotrypsin C variant Q48R, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant R254Q	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	15.5	0.0152	1 × 10³	pH 8, 22 °C	Open record: chymotrypsin C variant R254Q, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant R254W	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	16.6	0.0151	1.1 × 10³	pH 8, 22 °C	Open record: chymotrypsin C variant R254W, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant R37Q	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	14.4	0.0204	710	pH 8, 22 °C	Open record: chymotrypsin C variant R37Q, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant V235I	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	12.6	0.0158	800	pH 8, 22 °C	Open record: chymotrypsin C variant V235I, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
chymotrypsin Cvariant V250E	Homo sapiens	N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide	1.4	1.539	0.91	pH 8, 22 °C	Open record: chymotrypsin C variant V250E, N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide