Values CatLog read from this paper
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase
PMID 20421396doi:10.1128/aac.00197-10Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 15 records (45 values) from this paper: KPC-2 beta-lactamase from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| KPC-2 beta-lactamase | Klebsiella pneumoniae | Cefotaxime | 142 | 0.207 | 700 | pH 7.4 | Open record: KPC-2 beta-lactamase, Cefotaxime |
| KPC-2 beta-lactamase | Klebsiella pneumoniae | Cephalothin | 44 | 0.014 | 3.1 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase, Cephalothin |
| KPC-2 beta-lactamase | Klebsiella pneumoniae | Imipenem | 19 | 0.019 | 1 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase, Imipenem |
| KPC-2 beta-lactamase | Klebsiella pneumoniae | nitrocefin | 52 | 0.006 | 8.7 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase, nitrocefin |
| KPC-2 beta-lactamase | Klebsiella pneumoniae | Piperacillin | 51 | 0.015 | 3.4 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase, Piperacillin |
| KPC-2 beta-lactamasevariant T237A | Klebsiella pneumoniae | Cephalothin | 26 | 0.03 | 900 | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237A, Cephalothin |
| KPC-2 beta-lactamasevariant T237A | Klebsiella pneumoniae | Imipenem | 6.8 | 0.031 | 220 | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237A, Imipenem |
| KPC-2 beta-lactamasevariant T237A | Klebsiella pneumoniae | nitrocefin | 191 | 0.015 | 1.3 × 10⁴ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237A, nitrocefin |
| KPC-2 beta-lactamasevariant T237A | Klebsiella pneumoniae | Piperacillin | 42 | 0.012 | 3.5 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237A, Piperacillin |
| KPC-2 beta-lactamasevariant T237E | Klebsiella pneumoniae | nitrocefin | 92 | 0.167 | 600 | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237E, nitrocefin |
| KPC-2 beta-lactamasevariant T237S | Klebsiella pneumoniae | Cefotaxime | 43 | 0.168 | 260 | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237S, Cefotaxime |
| KPC-2 beta-lactamasevariant T237S | Klebsiella pneumoniae | Cephalothin | 65 | 0.018 | 3.6 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237S, Cephalothin |
| KPC-2 beta-lactamasevariant T237S | Klebsiella pneumoniae | Imipenem | 21 | 0.021 | 1 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237S, Imipenem |
| KPC-2 beta-lactamasevariant T237S | Klebsiella pneumoniae | nitrocefin | 50 | 0.005 | 1 × 10⁴ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237S, nitrocefin |
| KPC-2 beta-lactamasevariant T237S | Klebsiella pneumoniae | Piperacillin | 42 | 0.006 | 7 × 10³ | pH 7.4 | Open record: KPC-2 beta-lactamase variant T237S, Piperacillin |