Values CatLog read from this paper
Fluorinated substrates result in variable leakage of a reaction intermediate during catalysis by dehydroquinate synthase
PMID 21387027doi:10.1039/c0ob01141jOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (18 values) from this paper: dehydroquinate synthase (DHQS) from Actinidia chinensis, Escherichia coli, Pyrococcus furiosus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 9 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dehydroquinate synthase (DHQS) | Actinidia chinensis | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.3 | 0.0087 | 34 calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Actinidia chinensis | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.9 | 0.064 | 14 calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Actinidia chinensis | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.5 | 0.0032 | 160 calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 2.5 | 0.0016 | 1.6 × 10³ calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.3 | 0.021 | 14 calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 16 | 0.0057 | 2.8 × 10³ calc. | pH 6.8, 25 °C | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 3.3 | 0.002 | 1.6 × 10³ calc. | pH 6.7, 60 °C | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 1.3 | 0.029 | 45 calc. | pH 6.7, 60 °C | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 3 | 0.0037 | 810 calc. | pH 6.7, 60 °C | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |