EC 4.6.1.3: 3-dehydroquinate synthase
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CatLog read 9 records for EC 4.6.1.3 from 1 paper, for 3 organisms. Names in these papers: dehydroquinate synthase (DHQS).
EC 4.6.1.3 is no longer current; BRENDA: “transferred to EC 4.2.3.4”.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Fluorinated substrates result in variable leakage of a reaction intermediate during catalysis by dehydroquinate synthase | Actinidia chinensis, Escherichia coli and 1 more | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| dehydroquinate synthase (DHQS) | Actinidia chinensis | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.3 | 0.0087 | 34 calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Actinidia chinensis | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.9 | 0.064 | 14 calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Actinidia chinensis | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.5 | 0.0032 | 160 calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 2.5 | 0.0016 | 1.6 × 10³ calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 0.3 | 0.021 | 14 calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Escherichia coli | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 16 | 0.0057 | 2.8 × 10³ calc. | pH 6.8, 25 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 3.3 | 0.002 | 1.6 × 10³ calc. | pH 6.7, 60 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3R)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate | 1.3 | 0.029 | 45 calc. | pH 6.7, 60 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), (3S)-3-fluoro-3-deoxy-D-arabino-heptulosonate 7-phosphate |
| dehydroquinate synthase (DHQS) | Pyrococcus furiosus | 3-deoxy-D-arabino-heptulosonate 7-phosphate | 3 | 0.0037 | 810 calc. | pH 6.7, 60 °C | PMID 21387027 | Open record: dehydroquinate synthase (DHQS), 3-deoxy-D-arabino-heptulosonate 7-phosphate |