Values CatLog read from this paper
Live-cell DNMT3A "catalysome" mapping using engineered methyl-transfer pathways
PMID 42770327doi:10.1093/nar/gkag906Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (20 values) from this paper: DNMT3A from Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 10 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| DNMT3A | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dI-dC)∙poly(dI-dC) | 3.3 × 10⁻⁴ | 3.6 × 10⁻⁴ | 0.93 calc. | pH 7.4, 37 °C | Open record: DNMT3A, S-adenosyl-L-methionine |
| DNMT3A | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dG-dC)∙poly(dG-dC) | 8.1 × 10⁻⁵ | 3 × 10⁻⁴ | 0.27 calc. | pH 7.4, 37 °C | Open record: DNMT3A, S-adenosyl-L-methionine |
| DNMT3Avariant R887A | Mus musculus | Ado-6-azidecosubstrate poly(dI-dC)∙poly(dI-dC) | 2.8 × 10⁻⁵ | 4.4 × 10⁻⁴ | 0.063 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887A, Ado-6-azide |
| DNMT3Avariant R887A | Mus musculus | Ado-6-azidecosubstrate poly(dG-dC)∙poly(dG-dC) | 2.1 × 10⁻⁶ | 3.2 × 10⁻⁴ | 0.0066 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887A, Ado-6-azide |
| DNMT3Avariant R887A | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dI-dC)∙poly(dI-dC) | 3.3 × 10⁻⁴ | 3 × 10⁻⁴ | 1.1 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887A, S-adenosyl-L-methionine |
| DNMT3Avariant R887A | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dG-dC)∙poly(dG-dC) | 7.5 × 10⁻⁵ | 3.7 × 10⁻⁴ | 0.20 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887A, S-adenosyl-L-methionine |
| DNMT3Avariant R887G | Mus musculus | Ado-6-azidecosubstrate poly(dI-dC)∙poly(dI-dC) | 6.1 × 10⁻⁵ | 4.4 × 10⁻⁴ | 0.14 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887G, Ado-6-azide |
| DNMT3Avariant R887G | Mus musculus | Ado-6-azidecosubstrate poly(dG-dC)∙poly(dG-dC) | 5.17 × 10⁻⁶ | 4.2 × 10⁻⁴ | 0.012 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887G, Ado-6-azide |
| DNMT3Avariant R887G | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dI-dC)∙poly(dI-dC) | 2.28 × 10⁻⁴ | 7.2 × 10⁻⁴ | 0.32 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887G, S-adenosyl-L-methionine |
| DNMT3Avariant R887G | Mus musculus | S-adenosyl-L-methioninecosubstrate poly(dG-dC)∙poly(dG-dC) | 2.8 × 10⁻⁵ | 8.5 × 10⁻⁴ | 0.033 calc. | pH 7.4, 37 °C | Open record: DNMT3A variant R887G, S-adenosyl-L-methionine |