Values CatLog read from this paper
Use of docking peptides to design modular substrates with high efficiency for mitogen-activated protein kinase extracellular signal-regulated kinase
PMID 17918909doi:10.1021/cb700158qOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), p38α MAP kinase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-FQRKTLQRRNLKGLNLNL-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2.8 | 6 × 10⁻⁴ | 4.7 × 10³ | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-FQRKTLQRRNLKGLNLNL-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-LIPALRNMVRPKLTPA-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl; randomized MEK2 docking sequence) | 2.2 | 0.096 | 22 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-LIPALRNMVRPKLTPA-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl; randomized MEK2 docking sequence) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-MLARRKPVLPALTINP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2.3 | 0.0056 | 420 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-MLARRKPVLPALTINP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-MPKKKPTPIQLNP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2 | 0.0037 | 530 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-MPKKKPTPIQLNP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-PQKGRKPRDLELPL-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2.3 | 0.0044 | 530 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-PQKGRKPRDLELPL-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-TGPLSPGPF-(AOO)3-FQRKTLQRRNLKGLNLNL-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2.7 | 0.173 | 17 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-TGPLSPGPF-(AOO)3-FQRKTLQRRNLKGLNLNL-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-TGPLSPGPF-(AOO)3-MLARRKPVLPALTINP-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 3 | 0.338 | 8.3 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-TGPLSPGPF-(AOO)3-MLARRKPVLPALTINP-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-TGPLSPGPF-(AOO)3-MPKKKPTPIQLNP-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 2.8 | 0.344 | 8.3 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-TGPLSPGPF-(AOO)3-MPKKKPTPIQLNP-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| ERK1 (extracellular signal-regulated kinase 1, MAP kinase) | — | fluorescein-TGPLSPGPF-NH2 (N-terminal fluorescein, C-terminal amide; no docking peptide) | 4.2 | 0.127 | 32 | pH 7.2, 30 °C | Open record: ERK1 (extracellular signal-regulated kinase 1, MAP kinase), fluorescein-TGPLSPGPF-NH2 (N-terminal fluorescein, C-terminal amide; no docking peptide) |
| p38α MAP kinase | — | fluorescein-MLARRKPVLPALTINP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 16.7 | 0.03 | 550 | pH 7.2, 30 °C | Open record: p38α MAP kinase, fluorescein-MLARRKPVLPALTINP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| p38α MAP kinase | — | fluorescein-MPKKKPTPIQLNP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) | 9.5 | 0.065 | 145 | pH 7.2, 30 °C | Open record: p38α MAP kinase, fluorescein-MPKKKPTPIQLNP-(AOO)3-TGPLSPGPF-NH2 (AOO = 8-amino-3,6-dioxaoctanoyl) |
| p38α MAP kinase | — | fluorescein-TGPLSPGPF-NH2 (N-terminal fluorescein, C-terminal amide; no docking peptide) | 9.5 | 1.2 | 8.3 | pH 7.2, 30 °C | Open record: p38α MAP kinase, fluorescein-TGPLSPGPF-NH2 (N-terminal fluorescein, C-terminal amide; no docking peptide) |