Values CatLog read from this paper
Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant
PMID 9371090doi:10.1006/expr.1997.4221Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (16 values) from this paper: dihydrofolate reductase from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dihydrofolate reductasevariant S108A | Plasmodium falciparum | 7,8-dihydrofolate | 21 | 0.014 | 1.5 × 10³ | 25 °C | Open record: dihydrofolate reductase variant S108A, 7,8-dihydrofolate |
| dihydrofolate reductasevariant S108A | Plasmodium falciparum | reduced nicotinamide adenine dinucleotide phosphate | — | 0.009 | — | 25 °C | Open record: dihydrofolate reductase variant S108A, reduced nicotinamide adenine dinucleotide phosphate |
| dihydrofolate reductasevariant S108C | Plasmodium falciparum | 7,8-dihydrofolate | 12 | 0.023 | 500 | 25 °C | Open record: dihydrofolate reductase variant S108C, 7,8-dihydrofolate |
| dihydrofolate reductasevariant S108C | Plasmodium falciparum | reduced nicotinamide adenine dinucleotide phosphate | — | 0.009 | — | 25 °C | Open record: dihydrofolate reductase variant S108C, reduced nicotinamide adenine dinucleotide phosphate |
| dihydrofolate reductasevariant S108G | Plasmodium falciparum | 7,8-dihydrofolate | 23 | 0.02 | 1.1 × 10³ | 25 °C | Open record: dihydrofolate reductase variant S108G, 7,8-dihydrofolate |
| dihydrofolate reductasevariant S108G | Plasmodium falciparum | reduced nicotinamide adenine dinucleotide phosphate | — | 0.009 | — | 25 °C | Open record: dihydrofolate reductase variant S108G, reduced nicotinamide adenine dinucleotide phosphate |
| dihydrofolate reductasevariant S108Q | Plasmodium falciparum | 7,8-dihydrofolate | 37 | 0.05 | 700 | 25 °C | Open record: dihydrofolate reductase variant S108Q, 7,8-dihydrofolate |
| dihydrofolate reductasevariant S108Q | Plasmodium falciparum | reduced nicotinamide adenine dinucleotide phosphate | — | 0.014 | — | 25 °C | Open record: dihydrofolate reductase variant S108Q, reduced nicotinamide adenine dinucleotide phosphate |