Values CatLog read from this paper
pH dependence of the enzymatic processing of collagen I by MMP-1 (fibroblast collagenase), MMP-2 (gelatinase A), and MMP-14 ectodomain
PMID 20549272doi:10.1007/s00775-010-0680-8Open in Browse
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CatLog read 24 records (72 values) from this paper: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), MMP-2 (gelatinase A, matrix metalloproteinase 2) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-1 chain0-protonated | 0.21 | 0.0075 | 28 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-1 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-1 chain1-protonated | 0.66 | 0.0011 | 630 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-1 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-1 chain2-protonated | 1.83 | 0.016 | 120 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-1 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-1 chain3-protonated | 0.65 | 0.74 | 0.88 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-1 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-2 chain0-protonated | 16.9 | 0.011 | 1.6 × 10³ | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-2 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-2 chain1-protonated | 5.44 | 0.0028 | 1.9 × 10³ | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-2 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-2 chain2-protonated | 0.79 | 0.0024 | 330 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-2 chain |
| MMP-1 (fibroblast collagenase, matrix metalloproteinase 1) | — | collagen I α-2 chain3-protonated | 0.54 | 0.46 | 1.2 | 37 °C | Open record: MMP-1 (fibroblast collagenase, matrix metalloproteinase 1), collagen I α-2 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-1 chain0-protonated | 4.56 | 0.045 | 100 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-1 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-1 chain1-protonated | 0.3 | 8.6 × 10⁻⁴ | 360 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-1 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-1 chain2-protonated | 0.43 | 0.17 | 2.5 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-1 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-1 chain3-protonated | 10.41 | 0.12 | 88 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-1 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-2 chain0-protonated | 58.61 | 0.53 | 110 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-2 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-2 chain1-protonated | 0.089 | 2.5 × 10⁻⁴ | 350 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-2 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-2 chain2-protonated | 0.014 | 0.004 | 3.5 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-2 chain |
| MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14) | — | collagen I α-2 chain3-protonated | 4.09 | 0.14 | 30 | 37 °C | Open record: MMP-14 ectodomain (ect-MMP-14, membrane-type matrix metalloproteinase 14), collagen I α-2 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-1 chain0-protonated | 0.47 | 0.0027 | 170 | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-1 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-1 chain1-protonated | 0.019 | 3 × 10⁻⁴ | 63 | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-1 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-1 chain2-protonated | 0.68 | 7.7 × 10⁻⁴ | 880 | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-1 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-1 chain3-protonated | 1.1 | 0.32 | 3.4 | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-1 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-2 chain0-protonated | 9.89 | 0.0031 | 3.2 × 10³ | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-2 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-2 chain1-protonated | 5.79 | 0.0079 | 730 | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-2 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-2 chain2-protonated | 255.6 | 0.12 | 2.1 × 10³ | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-2 chain |
| MMP-2 (gelatinase A, matrix metalloproteinase 2) | Homo sapiens | collagen I α-2 chain3-protonated | 1.52 | 6.5 × 10⁻⁴ | 2.3 × 10³ | 37 °C | Open record: MMP-2 (gelatinase A, matrix metalloproteinase 2), collagen I α-2 chain |