Values CatLog read from this paper

Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin

PMID 11514228doi:10.1016/s1074-5521(01)00051-5Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 17 records (51 values) from this paper: APH(2″)-Ia, AAC(6′)-APH(2″).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Open record
AAC(6′)-APH(2″)	—	acetyl coenzyme Akanamycin A held at 100 µM (footnote d)	0.24	0.0072	34	Open record: AAC(6′)-APH(2″), acetyl coenzyme A
AAC(6′)-APH(2″)	—	acetyl coenzyme Akanamycin A held at 300 µM (footnote d); E. coli-expressed	1.2	0.038	31	Open record: AAC(6′)-APH(2″), acetyl coenzyme A
AAC(6′)-APH(2″)	—	adenosine 5′-triphosphateB. subtilis-expressed	0.17	0.064	2.7	Open record: AAC(6′)-APH(2″), adenosine 5′-triphosphate
AAC(6′)-APH(2″)	—	adenosine 5′-triphosphateE. coli-expressed	0.32	0.135	2.4	Open record: AAC(6′)-APH(2″), adenosine 5′-triphosphate
AAC(6′)-APH(2″)	—	kanamycin Acoupled detection: 4,4′-dithiodipyridine	0.69	0.011	63	Open record: AAC(6′)-APH(2″), kanamycin A
AAC(6′)-APH(2″)	—	kanamycin AATP held at 1 mM (footnote a); cosubstrate ATP	0.32	0.0047	68	Open record: AAC(6′)-APH(2″), kanamycin A
AAC(6′)-APH(2″)	—	kanamycin Acoupled detection: 4,4′-dithiodipyridine; E. coli-expressed	1.7	0.031	56	Open record: AAC(6′)-APH(2″), kanamycin A
APH(2″)-Ia	—	adenosine 5′-triphosphate	0.21	0.09	2.3	Open record: APH(2″)-Ia, adenosine 5′-triphosphate
APH(2″)-Ia	—	kanamycin A	0.24	0.006	40	Open record: APH(2″)-Ia, kanamycin A
APH(2″)-Iavariant K125A	—	adenosine 5′-triphosphate	0.24	0.1	2.4	Open record: APH(2″)-Ia variant K125A, adenosine 5′-triphosphate
APH(2″)-Iavariant K125A	—	kanamycin A	0.2	0.00653	31	Open record: APH(2″)-Ia variant K125A, kanamycin A
APH(2″)-Iavariant K13A	—	adenosine 5′-triphosphate	0.33	0.113	2.9	Open record: APH(2″)-Ia variant K13A, adenosine 5′-triphosphate
APH(2″)-Iavariant K13A	—	kanamycin A	0.28	0.0106	26	Open record: APH(2″)-Ia variant K13A, kanamycin A
APH(2″)-Iavariant K287A	—	adenosine 5′-triphosphate	0.23	0.094	2.4	Open record: APH(2″)-Ia variant K287A, adenosine 5′-triphosphate
APH(2″)-Iavariant K287A	—	kanamycin A	0.3	0.0088	34	Open record: APH(2″)-Ia variant K287A, kanamycin A
APH(2″)-Iavariant K52A	—	adenosine 5′-triphosphate	0.015	0.227	0.066	Open record: APH(2″)-Ia variant K52A, adenosine 5′-triphosphate
APH(2″)-Iavariant K52A	—	kanamycin A	0.017	0.00207	8.2	Open record: APH(2″)-Ia variant K52A, kanamycin A