Values CatLog read from this paper
Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase
PMID 16712772doi:10.1016/j.abb.2006.04.001Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 11 records (29 values) from this paper: NADP-dependent isocitrate dehydrogenase (mitochondrial) from Sus scrofa.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NADP-dependent isocitrate dehydrogenase (mitochondrial) | Sus scrofa | NAD+ | 0.76 | 17.9 | 0.0423 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial), NAD+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant D375N | Sus scrofa | NAD+ | 0.03 | 23.2 | 0.0011 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant D375N, NAD+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant D375N | Sus scrofa | NADP+ | 8.4 | 0.1329 | 60 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant D375N, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant K260Q | Sus scrofa | NAD+ | 0.47 | 31.2 | 0.0149 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant K260Q, NAD+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant K260Q | Sus scrofa | NADP+ | 1.7 | 0.2502 | 7 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant K260Q, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant K260R | Sus scrofa | NAD+ | 0.5 | 20.7 | 0.0242 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant K260R, NAD+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant K260R | Sus scrofa | NADP+ | 5.7 | 0.0378 | 150 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant K260R, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant K374Q | Sus scrofa | NADP+ | — | 0.0154 | 2.77 × 10³ | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant K374Q, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant T373A | Sus scrofa | NADP+ | — | 0.0062 | 60 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant T373A, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant T373S | Sus scrofa | NADP+ | — | 0.0055 | 4.71 × 10³ | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant T373S, NADP+ |
| NADP-dependent isocitrate dehydrogenase (mitochondrial)variant T373V | Sus scrofa | NADP+ | — | 0.0121 | 530 | pH 7.4, 25 °C | Open record: NADP-dependent isocitrate dehydrogenase (mitochondrial) variant T373V, NADP+ |