Values CatLog read from this paper
Structure-based characterization of canine-human chimeric uricases and its evolutionary implications
PMID 22481018doi:10.1016/j.biochi.2012.03.016Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: uricase (urate oxidase) from canine.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| uricase (urate oxidase) | canine | uric acid | 13.6 | 0.0085 | 1583 | pH 8.6, 25 °C | Open record: uricase (urate oxidase), uric acid |
| uricase (urate oxidase)variant A296V | canine | uric acid | 16.08 | 0.0064 | 2513 | pH 8.6, 25 °C | Open record: uricase (urate oxidase) variant A296V, uric acid |
| uricase (urate oxidase)variant A89T/G91A/V92M/H245L/E252A/M253I/R291K/A296V/A301S/K303R (UHC_H2) | canine | uric acid | 8.7 | 0.017 | 512 | pH 8.6, 25 °C | Open record: uricase (urate oxidase) variant A89T/G91A/V92M/H245L/E252A/M253I/R291K/A296V/A301S/K303R (UHC_H2), uric acid |
| uricase (urate oxidase)variant H245L/E252A/M253I/R291K/A296V/A301S/K303R (UHC, HU245-304) | canine | uric acid | 15.5 | 0.0065 | 2385 | pH 8.6, 25 °C | Open record: uricase (urate oxidase) variant H245L/E252A/M253I/R291K/A296V/A301S/K303R (UHC, HU245-304), uric acid |
| uricase (urate oxidase)variant R291K/A296V/A301S/K303R (HU291-304) | canine | uric acid | 16.78 | 0.0064 | 2622 | pH 8.6, 25 °C | Open record: uricase (urate oxidase) variant R291K/A296V/A301S/K303R (HU291-304), uric acid |