Values CatLog read from this paper
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli
PMID 19001118doi:10.1128/aac.00608-08Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 26 records (78 values) from this paper: AmpC-A, AmpC-B2 from Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AmpC-A | Escherichia coli | Cefotaxime | 0.2 | 0.025 | 8 | Open record: AmpC-A, Cefotaxime | |
| AmpC-A | Escherichia coli | Cefoxitin | 0.3 | 0.001 | 300 | Open record: AmpC-A, Cefoxitin | |
| AmpC-A | Escherichia coli | Ceftazidime | 0.5 | 0.07 | 7 | Open record: AmpC-A, Ceftazidime | |
| AmpC-A | Escherichia coli | Cephaloridine | 230 | 0.65 | 350 | Open record: AmpC-A, Cephaloridine | |
| AmpC-A | Escherichia coli | Cephalothin | 500 | 0.03 | 1.6 × 10⁴ | Open record: AmpC-A, Cephalothin | |
| AmpC-A | Escherichia coli | Imipenem | 0.1 | 0.01 | 10 | Open record: AmpC-A, Imipenem | |
| AmpC-Avariant S287N | Escherichia coli | Cefepime | 1.35 | 0.075 | 20 | Open record: AmpC-A variant S287N, Cefepime | |
| AmpC-Avariant S287N | Escherichia coli | Cefotaxime | 0.08 | 1 × 10⁻⁴ | 800 | Open record: AmpC-A variant S287N, Cefotaxime | |
| AmpC-Avariant S287N | Escherichia coli | Cefoxitin | 0.1 | 7 × 10⁻⁴ | 100 | Open record: AmpC-A variant S287N, Cefoxitin | |
| AmpC-Avariant S287N | Escherichia coli | Ceftazidime | 0.2 | 4 × 10⁻⁴ | 500 | Open record: AmpC-A variant S287N, Ceftazidime | |
| AmpC-Avariant S287N | Escherichia coli | Cephaloridine | 50 | 0.06 | 800 | Open record: AmpC-A variant S287N, Cephaloridine | |
| AmpC-Avariant S287N | Escherichia coli | Cephalothin | 65 | 0.0055 | 1.2 × 10⁴ | Open record: AmpC-A variant S287N, Cephalothin | |
| AmpC-Avariant S287N | Escherichia coli | Imipenem | 0.06 | 2 × 10⁻⁴ | 300 | Open record: AmpC-A variant S287N, Imipenem | |
| AmpC-B2 | Escherichia coli | Cefotaxime | 0.1 | 0.045 | 2 | Open record: AmpC-B2, Cefotaxime | |
| AmpC-B2 | Escherichia coli | Cefoxitin | 0.4 | 0.0015 | 300 | Open record: AmpC-B2, Cefoxitin | |
| AmpC-B2 | Escherichia coli | Ceftazidime | 0.3 | 0.27 | 1 | Open record: AmpC-B2, Ceftazidime | |
| AmpC-B2 | Escherichia coli | Cephaloridine | 240 | 0.95 | 250 | Open record: AmpC-B2, Cephaloridine | |
| AmpC-B2 | Escherichia coli | Cephalothin | 540 | 0.085 | 6 × 10³ | Open record: AmpC-B2, Cephalothin | |
| AmpC-B2 | Escherichia coli | Imipenem | 0.09 | 0.032 | 3 | Open record: AmpC-B2, Imipenem | |
| AmpC-B2variant S287N | Escherichia coli | Cefepime | 0.25 | 0.037 | 7 | Open record: AmpC-B2 variant S287N, Cefepime | |
| AmpC-B2variant S287N | Escherichia coli | Cefotaxime | 0.045 | 0.001 | 45 | Open record: AmpC-B2 variant S287N, Cefotaxime | |
| AmpC-B2variant S287N | Escherichia coli | Cefoxitin | 0.08 | 8 × 10⁻⁴ | 100 | Open record: AmpC-B2 variant S287N, Cefoxitin | |
| AmpC-B2variant S287N | Escherichia coli | Ceftazidime | 0.01 | 0.001 | 200 | Open record: AmpC-B2 variant S287N, Ceftazidime | |
| AmpC-B2variant S287N | Escherichia coli | Cephaloridine | 112 | 0.13 | 860 | Open record: AmpC-B2 variant S287N, Cephaloridine | |
| AmpC-B2variant S287N | Escherichia coli | Cephalothin | 10 | 0.045 | 200 | Open record: AmpC-B2 variant S287N, Cephalothin | |
| AmpC-B2variant S287N | Escherichia coli | Imipenem | 0.06 | 0.002 | 30 | Open record: AmpC-B2 variant S287N, Imipenem |