Values CatLog read from this paper
A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol
PMID 41949313doi:10.1128/mbio.03518-25Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (36 values) from this paper: ADC-227, ADC-30, ADC-33 from Acinetobacter baumannii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| ADC-227 | Acinetobacter baumannii | cefiderocol | 0.17 | 0.0078 | 22 | pH 7.2, 25 °C | Open record: ADC-227, cefiderocol |
| ADC-227 | Acinetobacter baumannii | ceftazidime | 0.47 | 0.0017 | 290 | pH 7.2, 25 °C | Open record: ADC-227, ceftazidime |
| ADC-227 | Acinetobacter baumannii | cephalothin | 220 | 0.0305 | 7.4 × 10³ | pH 7.2, 25 °C | Open record: ADC-227, cephalothin |
| ADC-227 | Acinetobacter baumannii | nitrocefin | 800 | 0.0473 | 1.7 × 10⁴ | pH 7.2, 25 °C | Open record: ADC-227, nitrocefin |
| ADC-30 | Acinetobacter baumannii | cefiderocol | 0.003 | 0.0136 | 0.2 | pH 7.2, 25 °C | Open record: ADC-30, cefiderocol |
| ADC-30 | Acinetobacter baumannii | ceftazidime | 0.28 | 0.0318 | 10 | pH 7.2, 25 °C | Open record: ADC-30, ceftazidime |
| ADC-30 | Acinetobacter baumannii | cephalothin | 2.26 × 10⁴ | 0.6911 | 3.27 × 10⁴ | pH 7.2, 25 °C | Open record: ADC-30, cephalothin |
| ADC-30 | Acinetobacter baumannii | nitrocefin | 5.5 × 10³ | 0.1942 | 2.82 × 10⁴ | pH 7.2, 25 °C | Open record: ADC-30, nitrocefin |
| ADC-33 | Acinetobacter baumannii | cefiderocol | 0.35 | 0.1236 | 2.8 | pH 7.2, 25 °C | Open record: ADC-33, cefiderocol |
| ADC-33 | Acinetobacter baumannii | ceftazidime | 2.2 | 0.0239 | 90 | pH 7.2, 25 °C | Open record: ADC-33, ceftazidime |
| ADC-33 | Acinetobacter baumannii | cephalothin | 310 | 0.0409 | 7.6 × 10³ | pH 7.2, 25 °C | Open record: ADC-33, cephalothin |
| ADC-33 | Acinetobacter baumannii | nitrocefin | 2.4 × 10³ | 0.1451 | 1.69 × 10⁴ | pH 7.2, 25 °C | Open record: ADC-33, nitrocefin |