CatLogenzyme kinetics catalog

Values CatLog read from this paper

Kinetic Mechanism of Nicotinamide N-Methyltransferase

PMID 30148963doi:10.1021/acs.biochem.8b00775Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (18 values) from this paper: nicotinamide N-methyltransferase (NNMT) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.1.1.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensnicotinamide0.0140.0034.7pH 8.6Open
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensquinoline0.01250.0170.735pH 8.6, 25 °COpen
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensquinoline0.0110.011.1pH 8.6Open
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensquinolineglobal fit to eq 1 (Table 2 row 1)0.0070.00920.76 calc.pH 8.6, 25 °COpen
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensquinolineglobal fit to eq 1 (Table 2 row 2)—0.015—pH 8.6, 25 °COpen
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensS-adenosylmethionine0.0080.010.75pH 8.6, 25 °COpen
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensS-adenosylmethionineglobal fit to eq 1 (Table 2 row 1)—0.012—pH 8.6, 25 °COpen
nicotinamide N-methyltransferase (NNMT)variant K100A/E101A/E103AHomo sapiensS-adenosylmethionineglobal fit to eq 1 (Table 2 row 2)0.0060.00680.88 calc.pH 8.6, 25 °COpen