Values CatLog read from this paper
Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion
PMID 12962487doi:10.1021/bi0342822Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 20 records (48 values) from this paper: Toho-1 β-lactamase from Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Toho-1 β-lactamase | Escherichia coli | benzylpenicillin | 68 | 0.023 | 3 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, benzylpenicillin |
| Toho-1 β-lactamase | Escherichia coli | cefcapene | 100 | 0.046 | 2.2 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefcapene |
| Toho-1 β-lactamase | Escherichia coli | cefdinir | 2.1 | 0.0014 | 1.5 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefdinir |
| Toho-1 β-lactamase | Escherichia coli | cefepime | — | — | 68 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefepime |
| Toho-1 β-lactamase | Escherichia coli | cefotaxime | 250 | 0.12 | 2.1 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefotaxime |
| Toho-1 β-lactamase | Escherichia coli | cefoxitin | 0.0061 | — | 0.76 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefoxitin |
| Toho-1 β-lactamase | Escherichia coli | cefpodoxime | — | — | 110 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cefpodoxime |
| Toho-1 β-lactamase | Escherichia coli | ceftazidime | 21 | 7.9 | 1.3 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, ceftazidime |
| Toho-1 β-lactamase | Escherichia coli | ceftizoxime | — | — | 120 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, ceftizoxime |
| Toho-1 β-lactamase | Escherichia coli | cephaloridine | 200 | 0.28 | 700 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cephaloridine |
| Toho-1 β-lactamase | Escherichia coli | cephalothin | 480 | 0.039 | 1.2 × 10⁴ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, cephalothin |
| Toho-1 β-lactamase | Escherichia coli | faropenem | 0.0096 | — | 1.9 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, faropenem |
| Toho-1 β-lactamase | Escherichia coli | imipenem | 0.0056 | — | 2.25 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, imipenem |
| Toho-1 β-lactamase | Escherichia coli | meropenem | 0.0089 | — | 100 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, meropenem |
| Toho-1 β-lactamase | Escherichia coli | moxalactam | 0.005 | — | 0.25 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, moxalactam |
| Toho-1 β-lactamase | Escherichia coli | nitrocefin | 160 | 0.059 | 2.7 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, nitrocefin |
| Toho-1 β-lactamase | Escherichia coli | piperacillin | 13 | 0.008 | 1.7 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, piperacillin |
| Toho-1 β-lactamase | Escherichia coli | S1090 | 21 | 0.0038 | 5.5 × 10³ | pH 7, 30 °C | Open record: Toho-1 β-lactamase, S1090 |
| Toho-1 β-lactamase | Escherichia coli | S4661 | 0.004 | — | 11 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, S4661 |
| Toho-1 β-lactamase | Escherichia coli | sulbactam | 0.18 | 3.1 × 10⁻⁴ | 580 | pH 7, 30 °C | Open record: Toho-1 β-lactamase, sulbactam |