Values CatLog read from this paper

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate

PMID 19237748doi:10.1107/s0907444908044028Open in Browse

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CatLog read 10 records (30 values) from this paper: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) from Mus musculus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.209

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)	Mus musculus	5α-androstan-3α-ol-17-one	0.073	6 × 10⁻⁴	122	25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21), 5α-androstan-3α-ol-17-one
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	4-androstene-3,17-dione	0.137	9 × 10⁻⁴	150	25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 4-androstene-3,17-dione
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5α-androstan-17α-ol-3-one	0.145	0.0048	30	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5α-androstan-17α-ol-3-one
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5α-androstan-17β-ol-3-one	0.38	0.027	14.2	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5α-androstan-17β-ol-3-one
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5α-androstan-3α-ol-17-one	0.22	0.0097	22	25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5α-androstan-3α-ol-17-one
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5α-pregnane-3α,20α-diol	0.15	0.08	1.7	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5α-pregnane-3α,20α-diol
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5β-androstan-17α-ol-3-one	0.055	0.0013	42	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5β-androstan-17α-ol-3-one
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	5β-pregnane-3α,20α-diol	0.18	0.0029	63	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, 5β-pregnane-3α,20α-diol
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	epitestosterone (epi-T)	0.25	0.018	13	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, epitestosterone (epi-T)
3(17)α-hydroxysteroid dehydrogenase (AKR1C21)variant G225P/G226P	Mus musculus	testosterone (TES)	0.04	0.023	1.7	pH 7, 25 °C	Open record: 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) variant G225P/G226P, testosterone (TES)