Values CatLog read from this paper
Structural insights into SETD3-mediated histidine methylation on β-actin
PMID 30785395doi:10.7554/elife.43676Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (54 values) from this paper: SETD3 (actin histidine N-methyltransferase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SETD3 (actin histidine N-methyltransferase) | Homo sapiens | S-adenosyl-L-methionine | 0.01122 | 1.11 × 10⁻⁴ | 101.0 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase), S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase) | Homo sapiens | β-actin | 0.01348 | 5.02 × 10⁻⁴ | 26.87 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase), β-actin |
| SETD3 (actin histidine N-methyltransferase)variant N256A | Homo sapiens | S-adenosyl-L-methionine | 0.00113 | 6.86 × 10⁻⁴ | 1.65 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256A, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant N256A | Homo sapiens | β-actin | 5.2 × 10⁻⁴ | 4.49 × 10⁻⁴ | 1.15 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256A, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant N256D | Homo sapiens | S-adenosyl-L-methionine | 6.7 × 10⁻⁴ | 1.65 × 10⁻⁴ | 4.03 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256D, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant N256D | Homo sapiens | β-actin | 9.7 × 10⁻⁴ | 3.05 × 10⁻⁴ | 3.17 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256D, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant N256Q | Homo sapiens | S-adenosyl-L-methionine | 0.00633 | 1.03 × 10⁻⁴ | 61.48 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256Q, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant N256Q | Homo sapiens | β-actin | 0.01082 | 7.84 × 10⁻⁴ | 13.8 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N256Q, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant N278A | Homo sapiens | S-adenosyl-L-methionine | 1.7 × 10⁻⁵ | 3.5 × 10⁻⁴ | 0.05 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N278A, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant N278A | Homo sapiens | β-actin | 1.7 × 10⁻⁵ | 4.7 × 10⁻⁵ | 0.35 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant N278A, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant R215A | Homo sapiens | S-adenosyl-L-methionine | 0.00365 | 1.65 × 10⁻⁴ | 22.12 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R215A, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant R215A | Homo sapiens | β-actin | 0.00353 | 0.001087 | 3.25 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R215A, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant R316A | Homo sapiens | S-adenosyl-L-methionine | 0.00407 | 1.49 × 10⁻⁴ | 27.3 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R316A, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant R316A | Homo sapiens | β-actin | 0.00288 | 0.001115 | 2.58 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R316A, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant R75A | Homo sapiens | S-adenosyl-L-methionine | 2.7 × 10⁻⁴ | 0.003601 | 0.067 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R75A, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant R75A | Homo sapiens | β-actin | 3.3 × 10⁻⁵ | 5.65 × 10⁻⁴ | 0.067 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant R75A, β-actin |
| SETD3 (actin histidine N-methyltransferase)variant Y313F | Homo sapiens | S-adenosyl-L-methionine | 0.00162 | 0.006543 | 0.25 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant Y313F, S-adenosyl-L-methionine |
| SETD3 (actin histidine N-methyltransferase)variant Y313F | Homo sapiens | β-actin | 3.7 × 10⁻⁴ | 5.81 × 10⁻⁴ | 0.63 | pH 7.2, 37 °C | Open record: SETD3 (actin histidine N-methyltransferase) variant Y313F, β-actin |