Values CatLog read from this paper
Disease associated missense substitutions disrupt structural stability and catalytic function of 4-hydroxyphenylpyruvate dioxygenase
PMID 42140431doi:10.1016/j.jbc.2026.113158Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 7 records (21 values) from this paper: 4-hydroxyphenylpyruvate dioxygenase (HPPD) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 4-hydroxyphenylpyruvate dioxygenase (HPPD) | Homo sapiens | 4-hydroxyphenylpyruvate | 1.4 | 0.06 | 21 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD), 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant A268V | Homo sapiens | 4-hydroxyphenylpyruvate | 1.5 | 0.07 | 21 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant A268V, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant A33T | Homo sapiens | 4-hydroxyphenylpyruvate | 0.6 | 0.06 | 9 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant A33T, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant N241S | Homo sapiens | 4-hydroxyphenylpyruvate | 2.2 | 0.03 | 83 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant N241S, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant R113Q | Homo sapiens | 4-hydroxyphenylpyruvate | 1.1 | 0.03 | 34 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant R113Q, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant V212M | Homo sapiens | 4-hydroxyphenylpyruvate | 0.4 | 0.009 | 38 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant V212M, 4-hydroxyphenylpyruvate |
| 4-hydroxyphenylpyruvate dioxygenase (HPPD)variant V340L | Homo sapiens | 4-hydroxyphenylpyruvate | 2.1 | 0.19 | 12 | pH 6.5, 37 °C | Open record: 4-hydroxyphenylpyruvate dioxygenase (HPPD) variant V340L, 4-hydroxyphenylpyruvate |