Values CatLog read from this paper
Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase
PMID 18627175doi:10.1021/bi800212bOpen in Browse
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CatLog read 9 records (27 values) from this paper: D-3-phosphoglycerate dehydrogenase (PGDH) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| D-3-phosphoglycerate dehydrogenase (PGDH)variant D463A | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 720 | 0.14 | 5 × 10³ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant D463A, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 1111 | 0.114 | 1 × 10⁴ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V/G317V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 2805 | 0.61 | 5 × 10³ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V/G317V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V/G318V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 2827 | 0.47 | 6 × 10³ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V/G318V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G317V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 2111 | 0.165 | 1.3 × 10⁴ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G317V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G317V/G318V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 605 | 0.22 | 3 × 10³ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G317V/G318V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant G318V | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 2349 | 0.203 | 1.2 × 10⁴ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G318V, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant N481A | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 603 | 0.12 | 5 × 10³ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant N481A, hydroxypyruvic acid phosphate |
| D-3-phosphoglycerate dehydrogenase (PGDH)variant Y461A | Mycobacterium tuberculosis | hydroxypyruvic acid phosphate | 2754 | 0.27 | 1 × 10⁴ | pH 7.5 | Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant Y461A, hydroxypyruvic acid phosphate |