EC 1.1.1.95: phosphoglycerate dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 133 records for EC 1.1.1.95 from 11 papers, for 11 organisms. Names in these papers: D-3-phosphoglycerate dehydrogenase, D-3-phosphoglycerate dehydrogenase (PHGDH), D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), D-3-phosphoglycerate dehydrogenase (PGDH) and 11 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 124 records for EC 1.1.1.95 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.95 in Browse.

Papers

Papers with records for EC 1.1.1.95
Paper	Organisms	Records
Identification of amino acid residues contributing to the mechanism of cooperativity in Escherichia coli D-3-phosphoglycerate dehydrogenase	Escherichia coli	41
The contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase	Escherichia coli	17
Comparison of Type 1 D-3-phosphoglycerate dehydrogenases reveals unique regulation in pathogenic Mycobacteria	Bacillus subtilis, Corynebacterium glutamicum and 5 more	14
Post-translational regulation of human D-3-phosphoglycerate dehydrogenase in Alzheimer's disease	Homo sapiens	13
Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis	Arabidopsis thaliana	12
Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase	Mycobacterium tuberculosis	9
Determinants of substrate specificity in D-3-phosphoglycerate dehydrogenase. Conversion of the M. tuberculosis enzyme from one that does not use α-ketoglutarate as a substrate to one that does	Escherichia coli, Mycobacterium tuberculosis	9
Molecular cloning and functional analysis of nine cinnamyl alcohol dehydrogenase family members in Populus tomentosa	Populus tomentosa	6
Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate	Homo sapiens	6
Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase	Saccharomyces cerevisiae	4
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria	Escherichia coli	2

Records

Records for EC 1.1.1.95 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
3-phosphoglycerate dehydrogenase (SerA)	Escherichia coli	3-phosphoglycerate	0.55	1.2	0.5	pH 8.8, 37 °C	PMID 8550422	Open record: 3-phosphoglycerate dehydrogenase (SerA), 3-phosphoglycerate
3-phosphoglycerate dehydrogenase (SerA)	Escherichia coli	3-phosphohydroxypyruvate	27.8	0.0032	8.7 × 10³	pH 7.5, 37 °C	PMID 8550422	Open record: 3-phosphoglycerate dehydrogenase (SerA), 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant A143V	Escherichia coli	α-ketoglutarate	8.6	1.19	7.2	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant A143V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant A144V	Escherichia coli	α-ketoglutarate	13.8	0.26	53	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant A144V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant A374V	Escherichia coli	α-ketoglutarate	11.7	0.35	33	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant A374V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant D317A	Escherichia coli	α-ketoglutarate	4.6	1.6	2.9	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant D317A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant D386A	Escherichia coli	α-ketoglutarate	13.1	0.35	37	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant D386A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E299A	Escherichia coli	α-ketoglutarate	4.9	1.99	2.5	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E299A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E302A	Escherichia coli	α-ketoglutarate	11.2	0.3	37	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E302A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E307A	Escherichia coli	α-ketoglutarate	12.3	1.77	6.9	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E307A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E345A	Escherichia coli	α-ketoglutarate	11.9	0.76	16	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E345A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E360A	Escherichia coli	α-ketoglutarate	10.8	0.66	16	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E360A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant E387A	Escherichia coli	α-ketoglutarate	12.8	0.28	46	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant E387A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant G145V	Escherichia coli	α-ketoglutarate	8.7	7.2	1.2	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant G145V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant G336V	Escherichia coli	α-ketoglutarate	9.9	0.19	52	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant G336V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant G337V	Escherichia coli	α-ketoglutarate	4.9	0.64	7.7	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant G337V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant G349V	Escherichia coli	α-ketoglutarate	6	0.69	9	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant G349V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant G362V	Escherichia coli	α-ketoglutarate	6.4	0.68	9.4	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant G362V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant H335A	Escherichia coli	α-ketoglutarate	7.8	0.79	9.8	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant H335A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant H344A	Escherichia coli	α-ketoglutarate	9.8	0.23	43	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant H344A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant K141A	Escherichia coli	3-phosphohydroxypyruvate	0.22	0.11	2	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant K141A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant K141A	Escherichia coli	α-ketoglutarate	0.33	1	0.33	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant K141A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant K141A	Escherichia coli	α-ketoglutarate	3.2	—	—	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant K141A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant K311A	Escherichia coli	α-ketoglutarate	5.2	12	0.4	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant K311A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant K39A	Escherichia coli	3-phosphohydroxypyruvate	15.2	0.04	380	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant K39A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant K39A	Escherichia coli	α-ketoglutarate	14.2	0.55	26	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant K39A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant N303A	Escherichia coli	α-ketoglutarate	12.4	1.41	8.9	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant N303A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant N303A/K311A	Escherichia coli	α-ketoglutarate	9.6	13.1	0.7	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant N303A/K311A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant N346A	Escherichia coli	α-ketoglutarate	14.9	0.39	38	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant N346A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant N364A	Escherichia coli	α-ketoglutarate	11.8	0.29	41	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant N364A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant Native (4CA)	Escherichia coli	α-ketoglutarate	13.5	0.49	28	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant Native (4CA), α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant P348A	Escherichia coli	α-ketoglutarate	9.3	0.58	16	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant P348A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant PGDH4C/A	Escherichia coli	3-phosphohydroxypyruvate	31.3	0.042	750	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant PGDH4C/A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant PGDH4C/A	Escherichia coli	α-ketoglutarate	31.3	0.63	50	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant PGDH4C/A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant Q298A	Escherichia coli	α-ketoglutarate	11.5	1.41	8.2	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant Q298A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant Q301A	Escherichia coli	α-ketoglutarate	10.6	4.78	2.2	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant Q301A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant Q361A	Escherichia coli	α-ketoglutarate	9	0.47	19	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant Q361A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant Q375A	Escherichia coli	α-ketoglutarate	18.7	0.49	38	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant Q375A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant R240A	Escherichia coli	3-phosphohydroxypyruvate	0.11	1.5	0.073	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R240A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant R240A	Escherichia coli	α-ketoglutarate	0.16	3.3	0.048	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R240A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant R338A	Escherichia coli	α-ketoglutarate	5.8	0.33	18	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant R338A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant R347A	Escherichia coli	α-ketoglutarate	12.1	0.45	27	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant R347A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant R60A	Escherichia coli	3-phosphohydroxypyruvate	0.51	0.043	12	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R60A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant R60A	Escherichia coli	α-ketoglutarate	0.95	0.95	1	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R60A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant R62A	Escherichia coli	3-phosphohydroxypyruvate	13.9	0.3	46	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R62A, 3-phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenasevariant R62A	Escherichia coli	α-ketoglutarate	11.8	2.3	5.1	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant R62A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S107A	Escherichia coli	α-ketoglutarate	9	0.97	9	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S107A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S107A/S111A	Escherichia coli	α-ketoglutarate	11.4	6.6	1.7	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S107A/S111A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S111A	Escherichia coli	α-ketoglutarate	7.5	4.33	1.7	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S111A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S111A/K311A	Escherichia coli	α-ketoglutarate	4.2	320	0.026	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S111A/K311A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S296A	Escherichia coli	α-ketoglutarate	7.4	1.37	5.4	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S296A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S316A	Escherichia coli	α-ketoglutarate	11.5	0.63	18	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S316A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S323A	Escherichia coli	α-ketoglutarate	11	0.68	16	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S323A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant S373A	Escherichia coli	α-ketoglutarate	11.9	0.72	17	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant S373A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant T297A	Escherichia coli	α-ketoglutarate	7	16.9	0.4	pH 7.5	PMID 16363798	Open record: D-3-phosphoglycerate dehydrogenase variant T297A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant W139A	Escherichia coli	α-ketoglutarate	0.116	3.2	0.037	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant W139A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant W139F	Escherichia coli	α-ketoglutarate	5.5	1.6	5.2	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant W139F, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant W139G	Escherichia coli	α-ketoglutarate	0.055	3.3	0.016	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant W139G, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant W139L	Escherichia coli	α-ketoglutarate	0.1	1.1	0.093	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant W139L, α-ketoglutarate
D-3-phosphoglycerate dehydrogenasevariant W139V	Escherichia coli	α-ketoglutarate	0.045	1.8	0.025	pH 7.5	PMID 10026144	Open record: D-3-phosphoglycerate dehydrogenase variant W139V, α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (ecPGDH)	Escherichia coli	phosphohydroxypyruvate	3.1	0.068	46	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (ecPGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (ecPGDH)	Escherichia coli	α-ketoglutarate	2.1	0.45	4.7	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (ecPGDH), α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (ecPGDH)variant K141R	Escherichia coli	phosphohydroxypyruvate	9.6	0.081	120	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (ecPGDH) variant K141R, phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (ecPGDH)variant K141R	Escherichia coli	α-ketoglutarate	0.49	5	0.098	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (ecPGDH) variant K141R, α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (mtPGDH)	Mycobacterium tuberculosis	phosphohydroxypyruvate	606	0.153	4 × 10³	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (mtPGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (mtPGDH)variant R132K	Mycobacterium tuberculosis	phosphohydroxypyruvate	458	0.015	3.1 × 10⁴	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (mtPGDH) variant R132K, phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (mtPGDH)variant R72A	Mycobacterium tuberculosis	α-ketoglutarate	16.1	53.1	0.3	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (mtPGDH) variant R72A, α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (mtPGDH)variant R72A/R132K	Mycobacterium tuberculosis	phosphohydroxypyruvate	490	0.169	2.9 × 10³	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (mtPGDH) variant R72A/R132K, phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (mtPGDH)variant R72L	Mycobacterium tuberculosis	α-ketoglutarate	4.3	30.6	0.14	pH 7	PMID 31344342	Open record: D-3-phosphoglycerate dehydrogenase (mtPGDH) variant R72L, α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (PGDH)variant D463A	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	720	0.14	5 × 10³	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant D463A, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	1111	0.114	1 × 10⁴	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V/G317V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	2805	0.61	5 × 10³	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V/G317V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G316V/G318V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	2827	0.47	6 × 10³	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G316V/G318V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G317V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	2111	0.165	1.3 × 10⁴	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G317V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G317V/G318V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	605	0.22	3 × 10³	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G317V/G318V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant G318V	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	2349	0.203	1.2 × 10⁴	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant G318V, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant N481A	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	603	0.12	5 × 10³	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant N481A, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PGDH)variant Y461A	Mycobacterium tuberculosis	hydroxypyruvic acid phosphate	2754	0.27	1 × 10⁴	pH 7.5	PMID 18627175	Open record: D-3-phosphoglycerate dehydrogenase (PGDH) variant Y461A, hydroxypyruvic acid phosphate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	3-phosphoglycerate	0.075	0.26	0.29 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), 3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	D-3-phosphoglycerate	1	1.2	0.83	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NAD+	—	0.022	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NAD+
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NADHcosubstrate oxaloacetate	—	0.004	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NADH
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NADHcosubstrate α-ketoglutarate	—	0.004	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NADH
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	oxaloacetate	0.177	6.5	0.027 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), oxaloacetate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	α-ketoglutarate	0.078	10.1	0.0078 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), α-ketoglutarate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant K289Q	Homo sapiens	D-3-phosphoglycerate	1.49	5	0.3	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant K289Q, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant K289R	Homo sapiens	D-3-phosphoglycerate	1.78	4.4	0.41	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant K289R, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S383A	Homo sapiens	D-3-phosphoglycerate	0.96	1.7	0.56	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S383A, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S383D	Homo sapiens	D-3-phosphoglycerate	1.29	2	0.64	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S383D, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S473A	Homo sapiens	D-3-phosphoglycerate	0.97	1.3	0.74	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S473A, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S473D	Homo sapiens	D-3-phosphoglycerate	1.13	1.6	0.7	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S473D, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S55A	Homo sapiens	D-3-phosphoglycerate	0.5	5.3	0.09	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S55A, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant S55D	Homo sapiens	D-3-phosphoglycerate	0.04	24.7	0.002	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant S55D, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant T60A	Homo sapiens	D-3-phosphoglycerate	1.13	1.8	0.62	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant T60A, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant T60D	Homo sapiens	D-3-phosphoglycerate	1.02	2.1	0.49	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant T60D, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant T78A	Homo sapiens	D-3-phosphoglycerate	0.92	3	0.3	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant T78A, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)variant T78D	Homo sapiens	D-3-phosphoglycerate	0.1	5.2	0.02	pH 7, 37 °C	PMID 41711160	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH) variant T78D, D-3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Bacillus subtilis	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	350	0.065	5.3 × 10³	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Bacillus subtilis	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	198	—	—	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Corynebacterium glutamicum	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	567	0.031	1.8 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Corynebacterium glutamicum	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	464	—	—	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Homo sapiens	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	311	0.127	2.4 × 10³	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Homo sapiens	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	41	0.003	1.4 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium marinum	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	341	0.041	8.3 × 10³	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium marinum	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	608	0.008	7.6 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium smegmatis	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	3.85 × 10³	0.292	1.32 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium smegmatis	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	1575	—	—	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium tuberculosis	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	2425	0.153	1.58 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Mycobacterium tuberculosis	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	1515	0.025	6.1 × 10⁴	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Streptomyces coelicolor	phosphohydroxypyruvate200 mM potassium phosphate (KPO4) buffer; pH 7.0	576	0.162	3.6 × 10³	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
D-3-phosphoglycerate dehydrogenase (Type 1 PGDH)	Streptomyces coelicolor	phosphohydroxypyruvate50 mM MOPS buffer; pH 7.0 (no phosphate)	194	—	—	pH 7	PMID 25698123	Open record: D-3-phosphoglycerate dehydrogenase (Type 1 PGDH), phosphohydroxypyruvate
phosphoglycerate dehydrogenase 1 (PGDH1)	Arabidopsis thaliana	3-phosphoglycerate	174.1	1.308	133.1	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 1 (PGDH1), 3-phosphoglycerate
phosphoglycerate dehydrogenase 1 (PGDH1)	Arabidopsis thaliana	3-phosphoglycerate	115.1	2.11	54.57	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 1 (PGDH1), 3-phosphoglycerate
phosphoglycerate dehydrogenase 1 (PGDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.39	446	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 1 (PGDH1), nicotinamide adenine dinucleotide (oxidized, NAD+)
phosphoglycerate dehydrogenase 1 (PGDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.377	305.7	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 1 (PGDH1), nicotinamide adenine dinucleotide (oxidized, NAD+)
phosphoglycerate dehydrogenase 2 (PGDH2)	Arabidopsis thaliana	3-phosphoglycerate	147.4	0.899	154.0	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 2 (PGDH2), 3-phosphoglycerate
phosphoglycerate dehydrogenase 2 (PGDH2)	Arabidopsis thaliana	3-phosphoglycerate	119.7	1.926	62.16	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 2 (PGDH2), 3-phosphoglycerate
phosphoglycerate dehydrogenase 2 (PGDH2)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.189	780.1	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 2 (PGDH2), nicotinamide adenine dinucleotide (oxidized, NAD+)
phosphoglycerate dehydrogenase 2 (PGDH2)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.271	442.6	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 2 (PGDH2), nicotinamide adenine dinucleotide (oxidized, NAD+)
phosphoglycerate dehydrogenase 3 (PGDH3)	Arabidopsis thaliana	3-phosphoglycerate	142.4	1.006	141.6	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 3 (PGDH3), 3-phosphoglycerate
phosphoglycerate dehydrogenase 3 (PGDH3)	Arabidopsis thaliana	3-phosphoglycerate	97	2.559	37.91	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 3 (PGDH3), 3-phosphoglycerate
phosphoglycerate dehydrogenase 3 (PGDH3)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.239	595.0	pH 8.1	PMID 24368794	Open record: phosphoglycerate dehydrogenase 3 (PGDH3), nicotinamide adenine dinucleotide (oxidized, NAD+)
phosphoglycerate dehydrogenase 3 (PGDH3)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized, NAD+)	—	0.551	176.2	pH 7.2	PMID 24368794	Open record: phosphoglycerate dehydrogenase 3 (PGDH3), nicotinamide adenine dinucleotide (oxidized, NAD+)
PtoCAD1	Populus tomentosa	Coniferyl aldehyde	45.42	0.02062	2203	pH 5, 30 °C	PMID 25096165	Open record: PtoCAD1, Coniferyl aldehyde
PtoCAD1	Populus tomentosa	Sinapyl aldehyde	16.59	0.0043	3859	pH 5, 30 °C	PMID 25096165	Open record: PtoCAD1, Sinapyl aldehyde
PtoCAD2	Populus tomentosa	Coniferyl aldehyde	7.78	0.01996	390.0	pH 6, 30 °C	PMID 25096165	Open record: PtoCAD2, Coniferyl aldehyde
PtoCAD2	Populus tomentosa	Sinapyl aldehyde	10.09	0.00985	1025	pH 6, 30 °C	PMID 25096165	Open record: PtoCAD2, Sinapyl aldehyde
PtoCAD8	Populus tomentosa	Coniferyl aldehyde	8.68	0.1461	59.43	pH 6, 30 °C	PMID 25096165	Open record: PtoCAD8, Coniferyl aldehyde
PtoCAD8	Populus tomentosa	Sinapyl aldehyde	3.63	1.970	1.842	pH 6, 30 °C	PMID 25096165	Open record: PtoCAD8, Sinapyl aldehyde
Ser3	Saccharomyces cerevisiae	2-oxoglutarate	0.2	0.049	4.3	pH 7.4, 30 °C	PMID 26774271	Open record: Ser3, 2-oxoglutarate
Ser3	Saccharomyces cerevisiae	3-phosphoglycerate	—	0.001	—	pH 8, 30 °C	PMID 26774271	Open record: Ser3, 3-phosphoglycerate
Ser33	Saccharomyces cerevisiae	2-oxoglutarate	0.25	0.054	6.6	pH 7.4, 30 °C	PMID 26774271	Open record: Ser33, 2-oxoglutarate
Ser33	Saccharomyces cerevisiae	3-phosphoglycerate	—	0.004	—	pH 8, 30 °C	PMID 26774271	Open record: Ser33, 3-phosphoglycerate