Values CatLog read from this paper
Repeated insertions at positions 261-280 in KPC-2 highlight a ceftazidime-avibactam resistance hotspot
PMID 42389611doi:10.1016/j.isci.2026.116514Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: KPC-2, KPC-261 from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| KPC-2 | Klebsiella pneumoniae | ceftazidime | 27 | 0.37 | 73 | Open record: KPC-2, ceftazidime | |
| KPC-2 | Klebsiella pneumoniae | imipenem | 153.3 | 0.54 | 280 | Open record: KPC-2, imipenem | |
| KPC-2 | Klebsiella pneumoniae | meropenem | 69.6 | 0.33 | 210 | Open record: KPC-2, meropenem | |
| KPC-261 | Klebsiella pneumoniae | ceftazidime | 2.5 | 0.27 | 9 | Open record: KPC-261, ceftazidime | |
| KPC-261 | Klebsiella pneumoniae | imipenem | 11.6 | 0.273 | 42 | Open record: KPC-261, imipenem | |
| KPC-261 | Klebsiella pneumoniae | meropenem | 10.7 | 0.113 | 95 | Open record: KPC-261, meropenem |