Values CatLog read from this paper
Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center
PMID 1396557doi:10.1002/j.1460-2075.1992.tb05439.xOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (39 values) from this paper: acetylcholinesterase (HuAChE) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase (HuAChE) | Homo sapiens | acetylthiocholine | 6.2 × 10³ | 0.14 | 4.67 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE), acetylthiocholine |
| acetylcholinesterase (HuAChE)variant D74E | Homo sapiens | acetylthiocholine | 7.3 × 10³ | 0.5 | 1.47 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant D74E, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant D74G | Homo sapiens | acetylthiocholine | 6 × 10³ | 0.63 | 9.5 × 10³ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant D74G, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant D74K | Homo sapiens | acetylthiocholine | 5.8 × 10³ | 4.5 | 1.3 × 10³ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant D74K, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant D74N | Homo sapiens | acetylthiocholine | 4.5 × 10³ | 0.58 | 7.7 × 10³ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant D74N, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant E202A | Homo sapiens | acetylthiocholine | 170 | 0.66 | 330 | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant E202A, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant E202D | Homo sapiens | acetylthiocholine | 250 | 0.25 | 1 × 10³ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant E202D, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant E202Q | Homo sapiens | acetylthiocholine | 930 | 0.35 | 2.7 × 10³ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant E202Q, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant F338A | Homo sapiens | acetylthiocholine | 2.8 × 10³ | 0.27 | 1.05 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant F338A, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant W286A | Homo sapiens | acetylthiocholine | 6.7 × 10³ | 0.28 | 2.38 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant W286A, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant Y337A | Homo sapiens | acetylthiocholine | 1.7 × 10³ | 0.14 | 1.18 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant Y337A, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant Y337F | Homo sapiens | acetylthiocholine | 6.2 × 10³ | 0.19 | 3.25 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant Y337F, acetylthiocholine |
| acetylcholinesterase (HuAChE)variant Y341A | Homo sapiens | acetylthiocholine | 5.3 × 10³ | 0.4 | 1.33 × 10⁴ | pH 8, 27 °C | Open record: acetylcholinesterase (HuAChE) variant Y341A, acetylthiocholine |