CatLogenzyme kinetics catalog

Values CatLog read from this paper

Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate

PMID 9753473doi:10.1021/bi980612kOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 86 records (258 values) from this paper: HIV-1 protease (PR), RSV protease (PR), AMV protease (PR) from human immunodeficiency virus type 1 (HIV-1), Rous sarcoma virus (RSV), avian myeloblastosis virus (AMV).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.23.16

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Ala-Val-Ile-Leu-Ala-Met-Thr-Met-Arg-Arg0.0830.018.3Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg1.420.009157Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-His-Met-Arg-Arg10.3043.3Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.30.0753.3Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg0.950.0195Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Arg-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.530.0926.7Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Pro-Phe-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.370.01328Open
AMV protease (PR)avian myeloblastosis virus (AMV)Pro-Val-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.050.0242.2Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.270.0338.3Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg0.370.02317Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg0.580.03417Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg0.930.03230Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg1.030.0252Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg0.830.0183Open
HIV-1 protease (PR)human immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.250.00928Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.20.0276.7Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg1.070.0912Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg0.470.0317Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg1.020.02443Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg1.150.02547Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg0.720.0172Open
HIV-1 protease (PR)variant G48V/L90Mhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.180.0118Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.750.05115Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg1.820.05433Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg2.220.0732Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg1.30.03340Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg2.550.03375Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg2.020.015135Open
HIV-1 protease (PR)variant I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.90.009100Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.130.0561.7Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg1.20.10812Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg0.620.03318Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg1.070.02445Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg1.10.02740Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg1.230.04428Open
HIV-1 protease (PR)variant R8Khuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.170.00723Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.0670.1050.67Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg0.60.1295Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg0.630.06110Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg0.60.03617Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg0.470.01337Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg0.50.01435Open
HIV-1 protease (PR)variant V32Ihuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.0830.018.3Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.530.04612Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg1.030.02738Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg1.220.04627Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg1.870.02867Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg1.730.05730Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg20.016125Open
HIV-1 protease (PR)variant V82Thuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.580.01345Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ala-Glu-Ala-Met-Arg0.330.0725Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Ile-Glu-Ala-Met-Arg1.60.07123Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Leu-Glu-Ala-Met-Arg1.60.06127Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Met-Glu-Ala-Met-Arg1.280.03142Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Phe-Glu-Ala-Met-Arg1.570.04633Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Arg-Val-Leu-Val-Glu-Ala-Met-Arg1.320.02453Open
HIV-1 protease (PR)variant V82T/I84Vhuman immunodeficiency virus type 1 (HIV-1)Pro-Ala-Phe-Val-Leu-Ala-Glu-Ala-Met-Arg0.320.01325Open
RSV protease (PR)variant A60MRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.0230.0590.33Open
RSV protease (PR)variant A60MRous sarcoma virus (RSV)Pro-Pro-Arg-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.060.1540.33Open
RSV protease (PR)variant H7ARous sarcoma virus (RSV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg1.20.006200Open
RSV protease (PR)variant H7ARous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-His-Met-Arg-Arg1.280.1578.3Open
RSV protease (PR)variant H7ARous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.280.0396.7Open
RSV protease (PR)variant H7ARous sarcoma virus (RSV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg0.750.006125Open
RSV protease (PR)variant I108VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.250.2541Open
RSV protease (PR)variant I108VRous sarcoma virus (RSV)Pro-Pro-Arg-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.630.4221.7Open
RSV protease (PR)variant I108VRous sarcoma virus (RSV)Pro-Pro-Phe-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.170.028.3Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Leu-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.090.2440.33Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Leu-Ser-Leu-Leu-Met-Thr-Met-Arg-Arg0.0180.0053.3Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg0.620.00878Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.1270.0383.3Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Leu-Met-Thr-Met-Arg-Arg0.1250.0176.7Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg0.420.00852Open
RSV protease (PR)variant I44VRous sarcoma virus (RSV)Pro-Val-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.0270.0271Open
RSV protease (PR)variant I71VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ile-Leu-Ala-Met-Thr-Met-Arg-Arg0.050.0086.7Open
RSV protease (PR)variant I71VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg1.030.007148Open
RSV protease (PR)variant I71VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.30.075Open
RSV protease (PR)variant I71VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg0.580.00872Open
RSV protease (PR)variant I71VRous sarcoma virus (RSV)Pro-Pro-Phe-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.470.01925Open
RSV protease (PR)variant L12VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg1.280.01680Open
RSV protease (PR)variant L12VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.230.063.3Open
RSV protease (PR)variant L12VRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg0.550.01247Open
RSV protease (PR)variant L12VRous sarcoma virus (RSV)Pro-Pro-Phe-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.30.01225Open
RSV protease (PR)variant R10KRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Phe-Leu-Ala-Met-Thr-Met-Arg-Arg4.630.038122Open
RSV protease (PR)variant R10KRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.170.1541Open
RSV protease (PR)variant R10KRous sarcoma virus (RSV)Pro-Pro-Ala-Val-Trp-Leu-Ala-Met-Thr-Met-Arg-Arg1.050.01762Open
RSV protease (PR)variant R10KRous sarcoma virus (RSV)Pro-Pro-Phe-Val-Ser-Leu-Ala-Met-Thr-Met-Arg-Arg0.370.03910Open